Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12671333 | 0.94 | GPR6 (0.36) | GPR6MCHR1KCNH2HSD11B1BRD4 | |
| SCHEMBL12671233 | 0.91 | GPR6 (0.39) | GPR6 | |
| SCHEMBL12671310 | 0.89 | PDE4A (0.38) | PDE4ACYP11B1CYP11B2EGLN2 | |
| SCHEMBL12671356 | 0.89 | PDE4A (0.35) | PDE4AGPR119KDM1ACYP11B1CYP11B2 | |
| SCHEMBL12671309 | 0.88 | GPR6 (0.34) | GPR6PDE4AMCHR1KCNH2CYP11B1 | |
| SCHEMBL12671322 | 0.87 | HSD11B1 (0.45) | HSD11B1BRD4BRD2KDM1AEGLN2 | |
| SCHEMBL12671330 | 0.86 | GPR6 (0.39) | GPR6 | |
| SCHEMBL7979711 | 0.86 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL12671368 | 0.83 | MDM2 (0.37) | GPR6HSD11B1EGLN2 | |
| SCHEMBL12671317 | 0.83 | HSD11B1 (0.38) | HSD11B1BRD4BRD2CYP11B2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377923-B2 | Triazole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | HSD11B1, HSD11B2, HSD3B1 | GPR6 4412/4885PDE4A 1846/4885MCHR1 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.