Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956251 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1LMNAELANE | |
| SCHEMBL13224465 | 0.79 | CYP1A2 (0.44) | ALDH1A1KMT2AMEN1LMNAELANE | |
| SCHEMBL12674685 | 0.74 | ALDH1A1 (0.76) | ALDH1A1KMT2ALMNAGSK3AGSK3B | |
| SCHEMBL26640417 | 0.74 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1ANPEPSMN1; SMN2 | |
| SCHEMBL30642153 | 0.74 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1ANPEPSMN1; SMN2 | |
| SCHEMBL14876494 | 0.73 | PTGDR2 (0.49) | ALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL15522229 | 0.72 | HDAC1 (0.53) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL522944 | 0.72 | PIN1 (0.68) | ALDH1A1KMT2AMEN1LMNAGSK3A | |
| SCHEMBL7371898 | 0.71 | ALDH1A1 (0.65) | ALDH1A1LMNAELANESMN1; SMN2GSK3A | |
| SCHEMBL6316299 | 0.71 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056985-A2 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2011-05-12 | — | — | WO | disclosed |