SCHEMBL126750

SCHEMBL126750

CC(C)/C(C(=O)O)=C(/C(=O)O)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
SLC7A5 Q01650 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125330 1.00 TP53 (0.41) TP53SLC7A5FFAR3LCKFYN
SCHEMBL125331 1.00 TP53 (0.41) TP53SLC7A5FFAR3LCKFYN
SCHEMBL304298 0.96 TP53 (0.39) TP53SLC7A5FFAR3LCKFYN
SCHEMBL304296 0.96 TP53 (0.39) TP53SLC7A5FFAR3LCKFYN
SCHEMBL5673269 0.83 TP53 (0.35) TP53
SCHEMBL14584344 0.83 FFAR3 (0.35) TP53FFAR3LCKFYN
SCHEMBL23115268 0.81 TP53 (0.33) TP53
SCHEMBL5611346 0.81 TP53 (0.33) TP53FFAR3LCKFYN
SCHEMBL15546440 0.81 TP53 (0.33) TP53
SCHEMBL23115267 0.81 TP53 (0.33) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310530-B1 COATING COMPOSITIONS ARKEMA INC (US) 2016-01-06 EP claimed
US-20120321685-A1 COMPOSITIONS CONTAINING OILS HAVING A SPECIFIC GRAVITY HIGHER THAN THE SPECIFIC GRAVITY OF WATER SOL-GEL TECHNOLOGIES LTD. (IL) 2012-12-20 US claimed
EP-1812479-B1 MODIFIED CHLORINATED CARBOXYLATED POLYOLEFINS AND THEIR USE AS ADHESION PROMOTERS EASTMAN CHEM CO (US) 2011-10-05 EP claimed
EP-2324812-A2 Composition exhibiting enhanced formulation stability and delivery of topical active ingredients Sol-Gel Technologies Ltd. (IL) 2011-05-25 EP claimed
EP-2000485-B1 Formaldehyde-free emulsion polymer dispersion composition including fully hydrolyzed polyvinyl alcohol as colloidal stabilizer provding improved heat resistance WACKER CHEMICAL CORP (US) 2010-08-11 EP claimed
EP-1604231-B9 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2009-01-07 EP claimed
EP-1304339-B2 Shear thinning vinyl acetate based polymer latex composition, especially for adhesives AIR PRODUCTS POLYMERS LP (US) 2008-08-27 EP claimed
EP-1604231-B1 PHOTOCHROMIC OCULAR DEVICES TRANSITIONS OPTICAL INC (US) 2008-07-02 EP claimed
EP-1682227-B1 PROCESS FOR MANUFACTURING A MASCARA WITH FIBER COMPONENTS COTY BV (NL) 2008-06-04 EP claimed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP claimed
EP-0702059-B1 Crosslinked polymer-powder compositions WACKER CHEMIE GMBH (DE) 1996-12-18 EP claimed
EP-0731207-A1 Binder for textile material Wacker-Chemie GmbH (DE) 1996-09-11 EP claimed
EP-0702059-A1 Crosslinked polymer-powder compositions Wacker-Chemie GmbH (DE) 1996-03-20 EP claimed
EP-0433957-B1 Use of aqueous copolymer dispersions incorporating acid salts of metals or free acids as adhesive WACKER CHEMIE GMBH (DE) 1995-04-19 EP claimed
EP-0621289-A1 Use of aqueous dispersions of vinyl ester copolymers as a glue Wacker-Chemie GmbH (DE) 1994-10-26 EP claimed
EP-0319016-B1 Treatment and after-treatment of metal with polyphenol compounds HENKEL CORP (US) 1994-06-22 EP claimed
EP-0319017-B1 Treatment and after-treatment of metal with carbohydrate-modified polyphenol compounds HENKEL CORP (US) 1994-04-13 EP claimed
EP-0573037-A1 Coating agent for coating aluminium Wacker-Chemie GmbH (DE) 1993-12-08 EP claimed
EP-0433957-A2 Use of aqueous copolymer dispersions incorporating acid salts of metals or free acids as adhesive WACKER-CHEMIE GMBH (DE) 1991-06-26 EP claimed
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120321685-A1 COMPOSITIONS CONTAINING OILS HAVING A SPECIFIC GRAVITY HIGHER THAN THE SPECIFIC GRAVITY OF WATER GNG2, COG5, SQLE TP53 1137/4885SLC7A5 3997/4885FFAR3 730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.