Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908478 | 0.78 | IDO1 (0.41) | BRD4IDO1CYP11B1CYP11B2ADRA1D | |
| SCHEMBL12534744 | 0.72 | TDP1 (0.43) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL988492 | 0.69 | TAAR1 (0.42) | IDO1CYP11B1CYP11B2PTGESALOX5 | |
| SCHEMBL1907330 | 0.67 | IDO1 (0.40) | IDO1CYP11B1CYP11B2ADRA1DADRA1A | |
| SCHEMBL1528676 | 0.67 | HSD17B10 (0.47) | IDO1PTGESALOX5GSK3BALDH1A1 | |
| SCHEMBL988943 | 0.66 | CYP11B1 (0.43) | CYP11B1CYP11B2PTGESALOX5ALDH1A1 | |
| SCHEMBL13780324 | 0.65 | HRH4 (0.51) | — | |
| SCHEMBL28904290 | 0.65 | HPGD (0.51) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13564332 | 0.64 | CASP6 (0.48) | BRD4IDO1CASP6ALDH1A1SMN1; SMN2 | |
| SCHEMBL28388976 | 0.63 | NCF1 (0.42) | PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056652-A1 | IMIDAZOLE DERIVATIVES AS IDO INHIBITORS | NEWLINK GENETICS (US) | 2011-05-12 | — | — | WO | disclosed |