Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PDXK | O00764 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16406420 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL12677316 | 0.84 | LMNA (0.57) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL20594900 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL12677154 | 0.76 | CYP3A4 (0.40) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10943402 | 0.76 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL4577077 | 0.76 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8155229 | 0.75 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL4576389 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Pyridoxine SCHEMBL3506 | 0.75 | HPGD (1.00) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Pyridoxine SCHEMBL30877002 | 0.75 | HPGD (1.00) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160199362-A1 | METHOD FOR THE TREATMENT, ALLEVIATION OF SYMPTOMS OF, RELIEVING, IMPROVING AND PREVENTING A COGNITIVE DISEASE, DISORDER OR CONDITION | ALCOBRA LTD. (IL) | 2016-07-14 | — | — | US | disclosed |
| WO-2011061743-A1 | METADOXINE AND DERIVATIVES THEREOF FOR USE IN THE TREATMENT OF INFLAMMATION AND IMMUNE-RELATED DISORDERS | ALCOBRA LTD. (IL) | 2011-05-26 | — | — | WO | disclosed |
| WO-2010150261-A1 | A METHOD FOR THE TREATMENT, ALLEVIATION OF SYMPTOMS OF, RELIEVING, IMPROVING AND PREVENTING A COGNITIVE DISEASE, DISORDER OR CONDITION | ALCOBRA LTD. (IL) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010013242-A1 | SUBSTITUTED PYRIDOXINE-LACTAM CARBOXYLATE SALTS | ALCOBRA LTD. (IL) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160199362-A1 | METHOD FOR THE TREATMENT, ALLEVIATION OF SYMPTOMS OF, RELIEVING, IMPROVING AND PREVENTING A COGNITIVE DISEASE, DISORDER OR CONDITION | ACHE, BCHE, GRIK5 | KDM4E 1328/4885ALDH1A1 886/4885HPGD 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.