SCHEMBL1267765

SCHEMBL1267765

CN(C)CCCN=C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3811926 0.93 NAAA (0.54)
SCHEMBL4859085 0.91 NAAA (0.58)
SCHEMBL14268360 0.91 NAAA (0.58)
SCHEMBL14268358 0.91 NAAA (0.58)
SCHEMBL1268079 0.84
SCHEMBL18937400 0.79 NAAA (0.50)
SCHEMBL3830223 0.79 CYP1A2 (0.82)
SCHEMBL988586 0.76 NAAA (0.52)
SCHEMBL18911845 0.76 MIF (0.52)
SCHEMBL301678 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0632815-B1 SEQUENTIAL DEGRADATION OF PROTEINS AND PEPTIDES FROM THE N-TERMINUS HOPE CITY (US) 2000-02-09 EP claimed
EP-0632815-A4 SEQUENTIAL DEGRADATION OF PROTEINS AND PEPTIDES FROM THE N-TERMINUS. HOPE CITY (US) 1996-08-21 EP claimed
US-5432093-A Sequential degradation of proteins and peptides from the N-terminus CITY OF HOPE (US) 1995-07-11 US claimed
EP-0632815-A1 SEQUENTIAL DEGRADATION OF PROTEINS AND PEPTIDES FROM THE N-TERMINUS CITY OF HOPE (US) 1995-01-11 EP claimed
WO-1994012538-A1 SEQUENTIAL DEGRADATION OF PROTEINS AND PEPTIDES FROM THE N-TERMINUS CITY OF HOPE (US) 1994-06-09 WO claimed
WO-2025077836-A1 IONIZABLE LIPIDS AND LIPID NANOPARTICLES FOR RNA DELIVERY BEIGENE SWITZERLAND GMBH (CH) 2025-04-17 WO disclosed
EP-4508048-A1 INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY Politechnika Gdanska (PL) 2025-02-19 EP disclosed
EP-3383378-B1 METHODS FOR INHIBITING CONVERSION OF CHOLINE TO TRIMETHYLAMINE (TMA) PROCTER & GAMBLE (US) 2024-04-17 EP disclosed
EP-3383377-B1 COMPOUNDS AND METHODS FOR INHIBITING PRODUCTION OF TRIMETHYLAMINE PROCTER & GAMBLE (US) 2024-04-17 EP disclosed
WO-2023182899-A1 INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY Politechnika Gdańska (PL) 2023-09-28 WO disclosed
WO-2023182899-A1 INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY Politechnika Gdańska (PL) 2023-09-28 WO disclosed
EP-3383376-B1 METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA) PROCTER & GAMBLE (US) 2021-05-12 EP disclosed
EP-0194112-B1 3-ARYL-OXYAZETIDINECARBOXAMIDES HAVING ANTI-MUSCLE TENSION, ANTI-MUSCLE SPASTICITY, ANTICONVULSANT AND ANTIEPILECTIC ACTIVITY A.H. ROBINS COMPANY, INCORPORATED (US) 1990-05-23 EP disclosed
US-4886738-A COLOR REVERSAL MATERIAL WITH IMPROVED PUSH DEVELOPABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-12-12 US disclosed
EP-0283041-A1 Direct positive silver halide photosensitive material and method for forming direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1988-09-21 EP disclosed
US-4772546-A THIADIAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1988-09-20 US disclosed
EP-0249239-A2 Process for the formation of direct positive images FUJI PHOTO FILM CO., LTD. (JP) 1987-12-16 EP disclosed
EP-0194112-A1 3-Aryl-oxyazetidinecarboxamides having anti-muscle tension, anti-muscle spasticity, anticonvulsant and antiepilectic activity A.H. ROBINS COMPANY, INCORPORATED (US) 1986-09-10 EP disclosed
EP-0182135-A2 Novel bis-(substituted amino) anthraquinones AMERICAN CYANAMID COMPANY (US) 1986-05-28 EP disclosed
US-4554242-A Method for processing color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-11-19 US disclosed