Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 8/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 4/20 | 0.48 |
| ▸ | BACH1 | O14867 | 2/20 | 0.47 |
| ▸ | MAFK | O60675 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859085 | 0.98 | NAAA (0.58) | NAAATRPA1MAOAMAOBCYP1A2 | |
| SCHEMBL14268360 | 0.98 | NAAA (0.58) | NAAATRPA1MAOAMAOBCYP1A2 | |
| SCHEMBL14268358 | 0.98 | NAAA (0.58) | NAAATRPA1MAOAMAOBCYP1A2 | |
| SCHEMBL1267765 | 0.93 | — | — | |
| SCHEMBL1268079 | 0.82 | — | — | |
| SCHEMBL484045 | 0.79 | MIF (0.68) | NAAATRPA1MIFBACH1MAFK | |
| SCHEMBL3095991 | 0.76 | CYP1A2 (0.48) | MAOAMAOBCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL1233523 | 0.76 | NAAA (0.74) | NAAATRPA1MIFBACH1MAFK | |
| SCHEMBL2149597 | 0.76 | NAAA (0.74) | NAAATRPA1MIFBACH1MAFK | |
| SCHEMBL7133119 | 0.76 | NAAA (0.74) | NAAATRPA1MIFBACH1MAFK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465880-B1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE TO TREAT DISORDERS ASSOCIATED WITH SOMATOSTATINE | IPSEN PHARMA (FR) | 2009-08-05 | — | — | EP | disclosed |
| CN-100462359-C | 5-sulfanyl-4H-1,2,4-triazole derivatives and their use as a medicament | SOD CONSEILS RECH APPLIC (FR) | 2009-02-18 | — | — | CN | disclosed |
| US-7332517-B2 | Derivatives of hydantoins, thiohydantoins, pyrimidinediones and thioxopyrimidinones, their preparation processes and their use as medicaments | Société de Conseils de Recheres et d'Applications Scientifiques (SCRAS) (FR) | 2008-02-19 | — | — | US | disclosed |
| US-7199145-B2 | Derivatives of hydantoins, thiohydantoins, pyrimidinediones and thioxopyrimidinones, their preparation processes and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D' 'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) (FR) | 2007-04-03 | — | — | US | disclosed |
| US-20050154039-A1 | 5-Sulphanyl-4h-1,2,4-triazole derivatives and their use as medicine | IPSEN PHARMA S.A.S. (FR) | 2005-07-14 | — | — | US | disclosed |
| CN-1617859-A | 5-sulfanyl-4H-1, 2, 4-triazole derivatives and their use as medicaments | SOD CONSEILS RECH APPLIC (FR) | 2005-05-18 | — | — | CN | disclosed |
| EP-1465880-A1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003045926-A1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154039-A1 | 5-Sulphanyl-4h-1,2,4-triazole derivatives and their use as medicine | SSTR3, SSTR1, SSTR5 | NAAA 4523/4885TRPA1 963/4885MAOA 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.