Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.81 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374 | 0.93 | HRH3 (0.67) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| Hydrochloric Acid SCHEMBL28688142 | 0.90 | HRH3 (0.64) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| Phosphine SCHEMBL25337730 | 0.90 | HRH3 (0.64) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| Bromide SCHEMBL3977215 | 0.90 | HRH3 (0.64) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| Bromide SCHEMBL3671914 | 0.90 | HRH3 (0.64) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL12679031 | 0.90 | HRH3 (1.00) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL32689849 | 0.82 | HRH3 (0.54) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| SCHEMBL659509 | 0.82 | HRH3 (0.82) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL23512760 | 0.81 | HRH3 (0.81) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL5915632 | 0.81 | TAAR1 (1.00) | HRH3TAAR1ALDH1A1TSHRPYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067440-B2 | Phosphonium salts derivatives and uses thereof | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-11-29 | — | — | US | disclosed |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | PI4K2A, PIP4K2A, PI4K2B | HRH3 3748/4885TAAR1 2924/4885ALDH1A1 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.