Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.67 |
| ▸ | NOS3 | P29474 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679031 | 0.91 | HRH3 (1.00) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL10050868 | 0.88 | HRH3 (0.67) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL12374 | 0.88 | HRH3 (0.67) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL6785180 | 0.86 | HRH3 (0.64) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL116611 | 0.86 | HRH3 (0.64) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| Phosphine SCHEMBL25337730 | 0.86 | HRH3 (0.64) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL12167936 | 0.86 | HRH3 (0.64) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL21723686 | 0.86 | HRH3 (0.64) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| Hydrochloric Acid SCHEMBL21821247 | 0.86 | HRH3 (0.64) | HRH3ALDH1A1TSHRTAAR1NOS3 | |
| SCHEMBL197287 | 0.86 | HRH3 (0.64) | HRH3ALDH1A1TSHRTAAR1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215762-A1 | Siloxane polymer containing tethered levofloxacin | NDSU RESEARCH FOUNDATION | 2009-08-27 | — | — | US | claimed |
| CN-117629955-A | Glucose self-calibration detection method | 宁波慈溪生物医学工程研究所 | 2024-03-01 | — | — | CN | disclosed |
| CN-117554315-A | Grape sugar accurate detection method for eliminating influence of interfering substances | 宁波慈溪生物医学工程研究所 | 2024-02-13 | — | — | CN | disclosed |
| US-20230371289-A1 | IMAGING DEVICE | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2023-11-16 | — | — | US | disclosed |
| US-20230338411-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS | RECODE THERAPEUTICS, INC. | 2023-10-26 | — | — | US | disclosed |
| CN-116920941-A | Silica-based catalyst loaded with ionic liquid and preparation method and application thereof | 山东海化集团有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-11779583-B2 | Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction | EMORY UNIVERSITY (US) | 2023-10-10 | — | — | US | disclosed |
| US-11779583-B2 | Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction | EMORY UNIVERSITY (US) | 2023-10-10 | — | — | US | disclosed |
| US-20210401836-A1 | TRICYCLIC AMINO CONTAINING COMPOUNDS FOR TREATMENT OR PREVENTION OF SYMPTOMS ASSOCIATED WITH ENDOCRINE DYSFUNCTION | EMORY UNIVERSITY (US) | 2021-12-30 | — | — | US | disclosed |
| WO-2020247662-A1 | DIBORONIC ACID COMPOUNDS AND METHODS OF MAKING AND USING THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-10 | — | — | WO | disclosed |
| EP-0825175-B1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0825175-A1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |
| EP-0542512-B1 | Oxygen-scavenging composition | MITSUBISHI GAS CHEMICAL CO (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5387368-A | A mixture of an aryl diamine, a transition metal compound and a phosphorus compound; prevents oxidation and decay of organic | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0542512-A1 | Oxygen-scavenging composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4791063-A | REMOVAL OF CONTAMINANTS FROM BIOLOGICAL FLUIDS | CUNO INCORPORATED (US) | 1988-12-13 | — | — | US | disclosed |
| US-4355116-A | ION EXCHANGE RESINS | ALLIED CORPORATION (US) | 1982-10-19 | — | — | US | disclosed |
| US-4118231-A | POLYMER CONTAINING QUATERNARY AMMONIUM GROUPS, ANTIFOAMING AGENTS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1978-10-03 | — | — | US | disclosed |
| US-4016128-A | Preparation of aqueous solutions of quaternary ammonium resins from di(tertiary amine) and 1,4-dihalobutene-2 | MONSANTO COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-3932564-A | CATIONIC POLYMERS, ELECTROGRAPHY | MONSANTO COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210401836-A1 | TRICYCLIC AMINO CONTAINING COMPOUNDS FOR TREATMENT OR PREVENTION OF SYMPTOMS ASSOCIATED WITH ENDOCRINE DYSFUNCTION | SHBG, ABAT, GLS | HRH3 623/4885ALDH1A1 3626/4885TSHR 61/4885 |
| US-11779583-B2 | Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction | SHBG, ABAT, GLS | HRH3 623/4885ALDH1A1 3626/4885TSHR 61/4885 |
| US-20090215762-A1 | Siloxane polymer containing tethered levofloxacin | PUF60, QARS1, SEPTIN7 | HRH3 4247/4885ALDH1A1 1791/4885TSHR 3245/4885 |
| US-20230338411-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY TO CELLS | CHMP4B, LIPA, NPC1L1 | HRH3 1656/4885ALDH1A1 4006/4885TSHR 2262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.