Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 7/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679745 | 0.86 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL13074418 | 0.78 | PGR (0.43) | LRRK2PGRKDM1ANR3C1AR | |
| SCHEMBL397364 | 0.77 | ALDH1A1 (0.43) | LRRK2PGRKDM1ANR3C1AR | |
| SCHEMBL4715808 | 0.77 | HSD17B2 (0.41) | LRRK2PGRKDM1ANR3C1AR | |
| SCHEMBL498595 | 0.75 | PGR (0.42) | LRRK2PGRKDM1ANR3C1AR | |
| SCHEMBL6972594 | 0.75 | PGR (0.44) | PGRNR3C1ARALDH1A1 | |
| SCHEMBL4718566 | 0.73 | APP (0.68) | PGRARALDH1A1APP | |
| 2,5-Thiophenedinitrile SCHEMBL996528 | 0.69 | — | — | |
| SCHEMBL12679744 | 0.69 | ADORA2A (0.54) | ALDH1A1MAPT | |
| SCHEMBL7733123 | 0.69 | PGR (0.43) | PGRKDM1ANR3C1ARTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120298980-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | UDC IRELAND LIMITED (IE) | 2012-11-29 | — | — | US | disclosed |
| US-8273467-B2 | Organic electroluminescent device | FUJIFILM CORPORATION (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20070202358-A1 | Organic electroluminescent device | FUJIFILM CORPORATION (JP) | 2007-08-30 | — | — | US | disclosed |