Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10170793 | 0.91 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3KLKB1HTR1A | |
| SCHEMBL12682899 | 0.79 | ALDH1A1 (0.39) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10170794 | 0.74 | GSK3B (0.46) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10170776 | 0.74 | PTPN1 (0.47) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10170791 | 0.71 | ALDH1A1 (0.49) | SLC6A4SLC6A2SLC6A3KLKB1 | |
| SCHEMBL11169652 | 0.70 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10170781 | 0.70 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11115696 | 0.69 | CHRNA1 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10170777 | 0.69 | CHRNA1 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5969867 | 0.67 | ACHE (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050918-A2 | TRICYCLIC FUSED RING INHIBITORS OF HEPATITIS C | PRESIDIO PHARMACEUTICAL, INC. (US) | 2012-04-19 | — | — | WO | disclosed |