Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15372097 | 0.90 | HCRTR1 (0.41) | PREPHCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL12682992 | 0.86 | HCRTR1 (0.39) | PREPHCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL10173010 | 0.84 | HCRTR1 (0.47) | PREPHCRTR1HCRTR2TSHRAADAT | |
| SCHEMBL12682947 | 0.81 | PRCP (0.42) | HCRTR1HCRTR2PRCP | |
| SCHEMBL12683010 | 0.81 | PREP (0.39) | PREPHCRTR1HCRTR2AADATTMEM97 | |
| SCHEMBL12682921 | 0.77 | CYP3A4 (0.52) | PRCP | |
| SCHEMBL12683233 | 0.77 | MALT1 (0.32) | — | |
| SCHEMBL15372096 | 0.76 | HCRTR1 (0.37) | PREPHCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL12683162 | 0.76 | HCRTR1 (0.37) | PREPHCRTR1HCRTR2ALDH1A1TSHR | |
| SCHEMBL12682910 | 0.75 | PREP (0.38) | PREPHCRTR1HCRTR2AADATTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050918-A2 | TRICYCLIC FUSED RING INHIBITORS OF HEPATITIS C | PRESIDIO PHARMACEUTICAL, INC. (US) | 2012-04-19 | — | — | WO | disclosed |