Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15372104 | 0.90 | CNR1 (0.33) | MALT1PIK3R1PIK3CA | |
| SCHEMBL12683057 | 0.86 | USP30 (0.32) | USP30 | |
| SCHEMBL12683240 | 0.80 | KMT2A (0.34) | MALT1KMT2AUSP30SMN1; SMN2PIK3R1 | |
| SCHEMBL15372102 | 0.80 | HCRTR1 (0.37) | KMT2AUSP30 | |
| SCHEMBL12683161 | 0.77 | KMT2A (0.38) | KMT2AUSP30 | |
| SCHEMBL15372100 | 0.77 | — | — | |
| SCHEMBL12683099 | 0.77 | PREP (0.39) | — | |
| SCHEMBL15372103 | 0.75 | CNR1 (0.34) | MALT1KMT2APIK3CA | |
| SCHEMBL12683101 | 0.73 | AAK1 (0.35) | KMT2A | |
| SCHEMBL205696 | 0.72 | KMT2A (0.47) | KMT2AUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012050918-A2 | TRICYCLIC FUSED RING INHIBITORS OF HEPATITIS C | PRESIDIO PHARMACEUTICAL, INC. (US) | 2012-04-19 | — | — | WO | disclosed |