SCHEMBL12684591 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	HPGD	P15428	6/20	0.47

▸	KMT2A	Q03164	4/20	0.47

▸	MEN1	O00255	2/20	0.47

▸	MAPT	P10636	1/20	0.46

▸	CHRM1	P11229	1/20	0.46

▸	HSP90AA1	P07900	4/20	0.40

▸	NPC1	O15118	3/20	0.39

▸	RAB9A	P51151	3/20	0.39

▸	LMNA	P02545	2/20	0.38

▸	SMN1; SMN2	Q16637	2/20	0.37

▸	ALDH1A1	P00352	3/20	0.36

▸	AKR1C1	Q04828	1/20	0.36

▸	GAA	P10253	1/20	0.36

▸	MAPK1	P28482	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12486948	1.00	HPGD (0.47)	HPGDKMT2AMEN1MAPTCHRM1
SCHEMBL12486947	1.00	HPGD (0.47)	HPGDKMT2AMEN1MAPTCHRM1
SCHEMBL12485722	0.93	KMT2A (0.41)	HPGDKMT2AMEN1MAPTCHRM1
SCHEMBL12485727	0.93	KMT2A (0.41)	HPGDKMT2AMEN1MAPTCHRM1
SCHEMBL12486525	0.93	HPGD (0.41)	HPGDKMT2AMEN1MAPTCHRM1
SCHEMBL12684589	0.93	HPGD (0.41)	HPGDKMT2AMEN1MAPTCHRM1
SCHEMBL12486521	0.93	HPGD (0.41)	HPGDKMT2AMEN1MAPTCHRM1
SCHEMBL12486605	0.88	KMT2A (0.39)	HPGDKMT2AMEN1MAPTCHRM1
SCHEMBL12486603	0.88	KMT2A (0.39)	HPGDKMT2AMEN1MAPTCHRM1
SCHEMBL12484667	0.85	ALDH1A1 (0.38)	KMT2AMEN1MAPTHSP90AA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012117421-A1	HISTONE DEACETYLASE INHIBITORS	ORCHID RESEARCH LABORATORIES LTD (IN)	2012-09-07	—	—	WO	disclosed