Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858206 | 0.77 | KDM4E (0.40) | DRD2OPRM1OPRK1 | |
| SCHEMBL16106910 | 0.76 | S1PR1 (0.36) | DRD2OPRM1OPRK1 | |
| SCHEMBL17913351 | 0.75 | DRD2 (0.36) | DRD2OPRM1OPRK1 | |
| SCHEMBL25698068 | 0.75 | DRD2 (0.36) | DRD2OPRM1OPRK1 | |
| SCHEMBL19604907 | 0.74 | S1PR1 (0.42) | DRD2 | |
| SCHEMBL23204070 | 0.73 | DRD2 (0.35) | DRD2 | |
| SCHEMBL4550235 | 0.73 | KDM4E (0.43) | DRD2 | |
| SCHEMBL14968300 | 0.73 | ALDH1A1 (0.41) | DRD2OPRM1OPRK1 | |
| SCHEMBL28137920 | 0.73 | DRD2 (0.35) | DRD2 | |
| SCHEMBL16118868 | 0.73 | DRD2 (0.33) | DRD2OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141757-A1 | LSD1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2024-07-04 | — | — | WO | disclosed |
| WO-2024020221-A1 | MODULATORS OF TYK2 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2012103059-A2 | BCL-2/BCL-XL INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-08-02 | — | — | WO | disclosed |