Pyridine

Pyridine

SCHEMBL1268592

CN1C=CC=CC1.c1ccncc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL190345 0.82
SCHEMBL28812505 0.79
Iodide SCHEMBL7099467 0.79
Water SCHEMBL7537804 0.79
SCHEMBL30661008 0.79
Hydrochloric Acid SCHEMBL1268973 0.79
Oxalic Acid SCHEMBL9096754 0.74
Oxalic Acid SCHEMBL10435669 0.74
Pyrrole SCHEMBL4467302 0.74
SCHEMBL28458457 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2124946-B1 THE USE OF N-METHYL PYRIDINIUM DERIVATIVES FOR HEPATOPROTECTION HEPENDO SP Z O O (PL) 2012-05-23 EP disclosed
US-7893095-B2 Treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury; 1,4-dimethylpyridinium Chloride; diabetes, metabolic syndrome, atherosclerosis TRIGENDO SP. Z O.O. (PL) 2011-02-22 US disclosed
EP-2124946-A1 THE USE OF QUATERNARY PYRIDINIUM COMPOUNDS FOR VASOPROTECTION AND/OR HEPATOPROTECTION Trigendo Sp. Z O.o. (PL) 2009-12-02 EP disclosed
US-20080221172-A1 Use of Quaternary Pyridinium Compounds for Vasoprotection and/or Hepatoprotection TRIGENDO SP. Z O.O. 2008-09-11 US disclosed
WO-2008104920-A1 THE USE OF QUATERNARY PYRIDINIUM COMPOUNDS FOR VASOPROTECTION AND/OR HEPATOPROTECTION TRIGENDO SP. Z O.O. (PL) 2008-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221172-A1 Use of Quaternary Pyridinium Compounds for Vasoprotection and/or Hepatoprotection PLPBP, PYGL, PRDX5 TSHR 2774/4885NAPRT 1915/4885TDP1 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.