Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23345459 | 0.78 | KMT2A (0.72) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL12820169 | 0.78 | MAPT (0.66) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL23345481 | 0.78 | KMT2A (0.70) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL8238479 | 0.77 | MAPT (0.61) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL23345456 | 0.77 | MAPT (0.83) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL11900786 | 0.77 | MAPT (0.67) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL11900782 | 0.77 | MAPT (0.67) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL23345514 | 0.76 | MAPT (0.71) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL23345473 | 0.76 | MAPT (0.71) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL11812589 | 0.76 | LMNA (0.94) | MAPTKMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012115575-A1 | DERIVATIVES FOR INDUCING OSTEOGENIC DIFFERENTIATION | BIOMATCELL AB (SE) | 2012-08-30 | — | — | WO | disclosed |