Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527861 | 0.90 | DDX3X (0.60) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL8239323 | 0.83 | MAPT (0.51) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL19002884 | 0.79 | MAPT (0.60) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL23345459 | 0.78 | KMT2A (0.72) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL23345481 | 0.78 | KMT2A (0.70) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL12685994 | 0.77 | MAPT (0.71) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL8238853 | 0.77 | DDX3X (0.61) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL23345514 | 0.76 | MAPT (0.71) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL23345473 | 0.76 | MAPT (0.71) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL23345486 | 0.76 | MAPT (0.69) | MAPTKMT2AMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790345-A1 | Triazin beta-secretase inhibitors | Esbatech AG (CH) | 2007-05-30 | — | — | EP | disclosed |
| WO-2007051333-A1 | TRIAZINE BETA-SECRETASE INHIBITORS | ONCALIS AG (CH) | 2007-05-10 | — | — | WO | disclosed |