Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29635163 | 0.89 | CTBP2 (0.61) | CTBP2POLBL3MBTL1NPC1CASP3 | |
| SCHEMBL7073775 | 0.89 | CTBP2 (0.61) | CTBP2POLBL3MBTL1NPC1CASP3 | |
| SCHEMBL11181344 | 0.84 | CTBP2 (0.60) | CTBP2POLBL3MBTL1NPC1CASP3 | |
| SCHEMBL25689281 | 0.82 | L3MBTL1 (0.57) | CTBP2POLBL3MBTL1NPC1CASP3 | |
| SCHEMBL2436067 | 0.80 | CTBP2 (0.56) | CTBP2POLBL3MBTL1NPC1CASP3 | |
| SCHEMBL3016501 | 0.79 | CTBP2 (0.54) | CTBP2POLBL3MBTL1NPC1CASP3 | |
| SCHEMBL12106782 | 0.79 | CTBP2 (0.54) | CTBP2POLBL3MBTL1NPC1CASP3 | |
| SCHEMBL12106784 | 0.79 | CTBP2 (0.54) | CTBP2POLBL3MBTL1NPC1CASP3 | |
| SCHEMBL13647128 | 0.78 | ALDH1A1 (0.39) | CTBP2POLBALDH1A1 | |
| SCHEMBL10979192 | 0.77 | CTBP2 (0.53) | CTBP2POLBL3MBTL1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012107163-A1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |