SCHEMBL1268613

SCHEMBL1268613

CC(N)COc1ccccc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.58
HTT P42858 3/20 0.58
ALDH1A1 P00352 6/20 0.56
KMT2A Q03164 2/20 0.56
PTK2B Q14289 1/20 0.56
HSD17B10 Q99714 6/20 0.51
HPGD P15428 4/20 0.51
ESR1 P03372 1/20 0.50
ITGB3 P05106 1/20 0.50
ITGA2B P08514 1/20 0.50
HMGB1 P09429 1/20 0.50
TSHR P16473 1/20 0.50
GGT1 P19440 1/20 0.50
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
BLM P54132 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
APEX1 P27695 1/20 0.50
MEN1 O00255 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15163056 0.87 HTT (0.65) KDM4EHTTKMT2AMEN1ABCB1
SCHEMBL477006 0.86 ALDH1A1 (0.59) KDM4EHTTALDH1A1KMT2APTK2B
Bicarbonate SCHEMBL29943829 0.85 ALDH1A1 (0.57) KDM4EHTTALDH1A1KMT2APTK2B
Bicarbonate SCHEMBL20694841 0.85 ALDH1A1 (0.57) KDM4EHTTALDH1A1KMT2APTK2B
Benzene SCHEMBL28043964 0.85 ALDH1A1 (0.57) KDM4EHTTALDH1A1KMT2APTK2B
SCHEMBL17799583 0.85 ALDH1A1 (0.57) KDM4EHTTALDH1A1KMT2APTK2B
Bicarbonate SCHEMBL236893 0.85 ALDH1A1 (0.57) KDM4EHTTALDH1A1KMT2APTK2B
SCHEMBL21505718 0.84 SLC6A3 (0.50) HTTALDH1A1KMT2AHSD17B10HPGD
SCHEMBL30174106 0.83 ALDH1A1 (0.56) KDM4EHTTALDH1A1KMT2APTK2B
SCHEMBL1552388 0.82 KDM4E (0.55) KDM4EHTTALDH1A1KMT2APTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1043376-B1 Use of anionic or cationic plasticizers with sulfonated polyesters in hot melt formulations NAT STARCH CHEM INVEST (US) 2004-12-08 EP claimed
EP-1043376-A2 Use of anionic or cationic plasticizers with sulfonated polyesters in hot melt formulations National Starch and Chemical Investment Holding Corporation (US) 2000-10-11 EP claimed
US-6001910-A COPOLYMER WITH SULFODIACIDS, DICARBOXYLIC ACIDS AND GLYCOLS AND DIAMINE GLYCOLS OR HYDROXY CARBOXYLIC ACIDS WITH PLASTICIZERS, TACKIFIERS, ANTIOXIDANTS AND WAX DILUENTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1999-12-14 US claimed
US-5750605-A Hot melt adhesives based on sulfonated polyesters NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1998-05-12 US claimed
EP-0364331-B1 Water-dissipatable polyester resins and coatings prepared therefrom EASTMAN KODAK CO (US) 1994-06-08 EP claimed
US-4990593-A Curable with amino resin; waterproof enamel; polyesteramides from aminocarboxylic acids, amino alcohols, sulfonated acids, glycols, diamines EASTMAN KODAK COMPANY (US) 1991-02-05 US claimed
EP-0409916-A1 WATER-DISSIPATABLE POLYESTER RESINS AND COATINGS PREPARED THEREFROM EASTMAN KODAK COMPANY (US) 1991-01-30 EP claimed
WO-1990003994-A2 WATER-DISSIPATABLE POLYESTER RESINS AND COATINGS PREPARED THEREFROM EASTMAN KODAK COMPANY (US) 1990-04-19 WO claimed
EP-0364331-A2 Water-dissipatable polyester resins and coatings prepared therefrom EASTMAN CHEMICAL COMPANY (US) 1990-04-18 EP claimed
US-4910292-A Having carbonyloxy linking groups EASTMAN KODAK COMPANY (US) 1990-03-20 US claimed
US-20160237258-A1 PROCESS FOR MAKING ELASTOMERIC COMPOSITIONS COMPRISING IONOMERS EASTMAN CHEMICAL COMPANY (US) 2016-08-18 US disclosed
US-20160237257-A1 ELASTOMERIC COMPOSITIONS COMPRISING IONOMERS EASTMAN CHEMICAL COMPANY (US) 2016-08-18 US disclosed
EP-2069449-B1 PRESSURE SENSITIVE ADHESIVE COMPOSITION EASTMAN CHEM CO (US) 2011-11-09 EP disclosed
US-7879942-B2 Wound dressings attached by pressure sensitive adhesive comprised of amphiphilic polyesters and humectant; strongly adhered when contacted with blood, sweat and/or other bodily fluids; easily peeled off by contacting with low ionic content liquid EASTMAN CHEMICAL COMPANY (US) 2011-02-01 US disclosed
CN-101522848-A Pressure sensitive adhesive composition EASTMAN CHEM CO (US) 2009-09-02 CN disclosed
US-4335220-A Sequestering agents and compositions produced therefrom EASTMAN KODAK COMPANY (US) 1982-06-15 US disclosed
US-4304901-A POLYCARBOXYLIC ACID OR POLYOL CONTAINING A NITROGEN CATION SULFONATE EASTMAN KODAK COMPANY (US) 1981-12-08 US disclosed
US-4304900-A DISULFONAMIDO COMPOUND EASTMAN KODAK COMPANY (US) 1981-12-08 US disclosed
US-4233196-A HOT MELT ADHESIVES, SIZING FOR TEXTILE FIBERS, WATER-SOLUBLE PACKAGING EASTMAN KODAK COMPANY (US) 1980-11-11 US disclosed
US-4073777-A Radiation crosslinkable polyester and polyesteramide compositions containing sulfonate groups in the form of a metallic salt and unsaturated groups EASTMAN KODAK COMPANY (US) 1978-02-14 US disclosed