SCHEMBL1268616

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1268734	0.88	L3MBTL1 (0.47)	TAAR1ATMSIGMAR1HTR2AHRH1
	SCHEMBL11044440	0.81	CA12 (0.50)	TAAR1SIGMAR1HTR2AHRH1CA12
	SCHEMBL27644720	0.79	ALDH1A1 (0.50)	TAAR1CA12CA2CA9L3MBTL1
	SCHEMBL9760728	0.79	CHRM5 (0.46)	SLC6A2NOS1NOS2PRMT1PRMT3
	SCHEMBL22542431	0.79	TMEM97 (0.48)	TAAR1SIGMAR1NOS1NOS2PRMT1
	SCHEMBL13358132	0.79	HTT (0.43)	TAAR1NOS2CA12CA2CA9
	SCHEMBL6241015	0.79	ALDH1A1 (0.46)	SIGMAR1NOS1NOS2PRMT1PRMT3
	SCHEMBL28320582	0.79	PRMT1 (0.39)	SIGMAR1NOS1NOS2PRMT1PRMT3
	SCHEMBL22542479	0.79	NOX1 (0.51)	SLC6A2SLC6A3L3MBTL1LMNABCHE
	SCHEMBL18233616	0.78	CA12 (0.38)	TAAR1CA12CA2CA9L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.