Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500290 | 0.75 | LMNA (0.61) | MAPTLMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL12686076 | 0.73 | MEN1 (0.71) | MAPTLMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL22737354 | 0.69 | LMNA (0.55) | MAPTLMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL23345483 | 0.66 | MAPT (0.79) | MAPTLMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL17200137 | 0.65 | POLB (0.60) | MAPTLMNASMN1; SMN2POLBTP53 | |
| SCHEMBL24490451 | 0.64 | HSD17B10 (0.63) | MAPTLMNASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL29345120 | 0.64 | POLB (0.58) | MAPTLMNASMN1; SMN2POLBTP53 | |
| SCHEMBL29345146 | 0.64 | LMNA (0.94) | MAPTLMNASMN1; SMN2HPGDPOLB | |
| SCHEMBL11810697 | 0.62 | LMNA (1.00) | MAPTLMNASMN1; SMN2POLBTP53 | |
| SCHEMBL12500068 | 0.61 | PIK3CA (0.81) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012115575-A1 | DERIVATIVES FOR INDUCING OSTEOGENIC DIFFERENTIATION | BIOMATCELL AB (SE) | 2012-08-30 | — | — | WO | disclosed |