SCHEMBL1268685

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1269909	0.93	TP53 (0.42)	GAAPKMEPHX2TP53MAPT
	SCHEMBL1268674	0.91	GAA (0.42)	GAAPKMEPHX2SCN9ATP53
	SCHEMBL1268669	0.90	GAA (0.45)	GAAPKMEPHX2SCN9ATP53
	SCHEMBL1269489	0.87	GAA (0.43)	GAAPKMEPHX2SCN9ATP53
	SCHEMBL1269770	0.86	GAA (0.42)	GAAPKMEPHX2SCN9ASCN5A
	SCHEMBL12900168	0.86	GAA (0.48)	GAAPKMEPHX2SCN9ASCN5A
	SCHEMBL1269830	0.85	GAA (0.43)	GAAPKMEPHX2SCN9AMAPT
	SCHEMBL1268492	0.84	GAA (0.45)	GAAPKMEPHX2SCN9ATP53
	SCHEMBL1269584	0.83	ALDH1A1 (0.43)	GAASCN9AMAPTHTTKMT2A
	SCHEMBL1269704	0.82	GAA (0.46)	GAAPKMEPHX2SCN9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.