SCHEMBL1269770

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1269953	0.93	CCKBR (0.42)	GAAEPHX2CCKBRMAPTMEN1
	SCHEMBL1269628	0.93	CCKBR (0.43)	GAAEPHX2CCKBRHTTMEN1
	SCHEMBL1268682	0.90	KMT2A (0.43)	GAAHTTMAPTMEN1ALDH1A1
	SCHEMBL1269726	0.89	CCR6 (0.35)	GAASCN9ASCN5ACCKBR
	SCHEMBL1269830	0.87	GAA (0.43)	GAAPKMEPHX2SCN9AHTT
	SCHEMBL1269603	0.86	GAA (0.45)	GAAPKMEPHX2SCN9ACCKBR
	SCHEMBL1268685	0.86	GAA (0.43)	GAAPKMEPHX2SCN9ASCN5A
	SCHEMBL1268674	0.86	GAA (0.42)	GAAPKMEPHX2SCN9AHTT
	SCHEMBL1268781	0.85	CCKBR (0.38)	GAASCN9ACCKBRALDH1A1HCRTR1
	SCHEMBL1269586	0.84	PIK3C3 (0.38)	GAASCN9ACCKBRHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.