SCHEMBL1268779

SCHEMBL1268779

CCC(O)C(C)C1OC1CC(C)(O)/C=C/C=C(\C)C1OC(=O)CC(O)CCC(C)(O)C(OC(C)=O)/C=C/C1C

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SF3B3 Q15393 10/20 0.77
HMGCR P04035 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23160740 1.00 SF3B3 (0.77) SF3B3HMGCR
SCHEMBL31571155 1.00 SF3B3 (0.77) SF3B3HMGCR
SCHEMBL12877545 1.00 SF3B3 (0.77) SF3B3HMGCR
SCHEMBL31204556 1.00 SF3B3 (0.77) SF3B3HMGCR
SCHEMBL23160741 1.00 SF3B3 (0.77) SF3B3HMGCR
SCHEMBL23160742 1.00 SF3B3 (0.77) SF3B3HMGCR
SCHEMBL12877326 1.00 SF3B3 (0.77) SF3B3HMGCR
SCHEMBL1267885 0.95 SF3B3 (0.71) SF3B3HMGCR
SCHEMBL16716722 0.95 SF3B3 (0.69) SF3B3HMGCR
SCHEMBL12877547 0.94 SF3B3 (0.70) SF3B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062404-A1 METHOD FOR PRODUCING MACROLIDE COMPOUND EISAI R&D MAN CO LTD (JP) 2026-03-05 US claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4570796-A1 METHOD FOR PRODUCING MACROLIDE COMPOUND Eisai R&D Management Co., Ltd. (JP) 2025-06-18 EP claimed
CN-119948022-A Process for producing macrolide compounds 卫材R&D管理有限公司 2025-05-06 CN claimed
WO-2024239281-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2024-11-28 WO claimed
WO-2024240173-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2024-11-28 WO claimed
EP-4426727-A2 SPECIFIC CONJUGATION OF AN ANTIBODY Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 EP claimed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 EP claimed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 WO claimed
CN-116096752-A anti-BCMA antibody-drug conjugates and methods of use thereof 卫材R&D管理有限公司 2023-05-09 CN claimed
EP-4161966-A1 ANTI-BCMA ANTIBODY-DRUG CONJUGATES AND METHODS OF USE Eisai R&D Management Co., Ltd. (JP) 2023-04-12 EP claimed
EP-4149483-A2 COMPOSITIONS AND METHODS FOR ENHANCING CANCER IMMUNOTHERAPY Fred Hutchinson Cancer Center (US) 2023-03-22 EP claimed
WO-2022078524-A4 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-12-08 WO claimed
WO-2022078524-A2 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-04-21 WO claimed
US-7655442-B2 Efficiently producing a macrolide compound, in which a cyclodextrin is made to be present in a culture broth of actinomycetes; antitumor agents EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-02-02 US claimed
US-20070155696-A1 Method for stabilizing macrolide compounds MERCIAN CORPORATION (JP) 2007-07-05 US claimed
EP-1710244-A1 METHOD OF STABILIZING MACROLIDE COMPOUND Eisai R&D Management Co., Ltd. (JP) 2006-10-11 EP claimed
US-7026352-B1 Physiologically active substances MERCIAN CORPORATION (JP) 2006-04-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070155696-A1 Method for stabilizing macrolide compounds MRPL21, ERG28, RPN1 SF3B3 2845/4885HMGCR 173/4885
US-20260062404-A1 METHOD FOR PRODUCING MACROLIDE COMPOUND CYP51A1, LAS1L, MRPL21 SF3B3 781/4885HMGCR 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.