SCHEMBL1268782

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1268492	0.89	GAA (0.45)	ALDH1A1SMN1; SMN2LMNAMAPTGAA
	SCHEMBL1268839	0.85	MEN1 (0.42)	MAPK1ALDH1A1SMN1; SMN2LMNAMEN1
	SCHEMBL1269715	0.85	MEN1 (0.43)	MAPK1ALDH1A1SMN1; SMN2LMNAMEN1
	SCHEMBL1269670	0.82	KMT2A (0.42)	ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL1269712	0.81	MAPK1 (0.40)	MAPK1ALDH1A1LMNAMEN1KMT2A
	SCHEMBL1269747	0.81	ALDH1A1 (0.42)	ALDH1A1LMNAMEN1KMT2AMAPT
	SCHEMBL1269717	0.80	MEN1 (0.44)	ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL1269909	0.80	TP53 (0.42)	MAPK1SMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL1269679	0.79	PTGDR2 (0.41)	ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
	SCHEMBL1269613	0.79	ALDH1A1 (0.41)	MAPK1ALDH1A1SMN1; SMN2LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.