SCHEMBL1269712

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1268840	0.89	KDM4E (0.43)	MAPK1L3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL1269747	0.86	ALDH1A1 (0.42)	L3MBTL1ALDH1A1KMT2AKDM4ELMNA
	SCHEMBL1268777	0.85	L3MBTL1 (0.41)	MAPK1L3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL1269787	0.84	ALDH1A1 (0.40)	MAPK1L3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL1269038	0.83	ALDH1A1 (0.42)	MAPK1L3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL1268782	0.81	MAPK1 (0.43)	MAPK1ALDH1A1KMT2AKDM4ELMNA
	SCHEMBL1269954	0.79	ALDH1A1 (0.42)	MAPK1L3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL1268492	0.78	GAA (0.45)	L3MBTL1ALDH1A1LMNAGAAPOLB
	SCHEMBL1269613	0.78	ALDH1A1 (0.41)	MAPK1L3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL1268887	0.77	ALDH1A1 (0.46)	ALDH1A1KMT2AKDM4ELMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.