SCHEMBL1268801

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1268653	0.90	SMN1; SMN2 (0.45)	ALDH1A1GLALMNASMN1; SMN2L3MBTL1
	SCHEMBL1269625	0.87	ALDH1A1 (0.51)	ALDH1A1GLALMNASMN1; SMN2L3MBTL1
	SCHEMBL1269442	0.86	ALDH1A1 (0.50)	ALDH1A1GLALMNASMN1; SMN2L3MBTL1
	SCHEMBL1269492	0.83	GAA (0.48)	ALDH1A1GLALMNASMN1; SMN2GAA
	SCHEMBL12931666	0.81	ALDH1A1 (0.45)	ALDH1A1GLALMNASMN1; SMN2GAA
	SCHEMBL1472315	0.78	ALDH1A1 (0.72)	ALDH1A1GLALMNASMN1; SMN2KMT2A
	SCHEMBL1268839	0.73	MEN1 (0.42)	ALDH1A1GLALMNASMN1; SMN2GAA
	SCHEMBL1269828	0.72	ALDH1A1 (0.45)	ALDH1A1LMNASMN1; SMN2L3MBTL1KMT2A
	SCHEMBL5307467	0.71	POLB (0.73)	ALDH1A1LMNASMN1; SMN2L3MBTL1GAA
	SCHEMBL5915275	0.69	POLB (0.71)	ALDH1A1LMNASMN1; SMN2L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.