⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783944 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL6640985 | 0.79 | — | — | |
| SCHEMBL698611 | 0.77 | — | — | |
| SCHEMBL25435787 | 0.77 | TSHR (0.54) | — | |
| SCHEMBL298254 | 0.77 | TSHR (0.68) | — | |
| SCHEMBL37351 | 0.77 | TSHR (0.54) | — | |
| SCHEMBL540805 | 0.76 | TSHR (0.48) | — | |
| Acetic Acid Isobutyl Ester SCHEMBL6360200 | 0.76 | TSHR (0.60) | — | |
| SCHEMBL540806 | 0.76 | TSHR (0.48) | — | |
| SCHEMBL128246 | 0.76 | TSHR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 583 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220184165-A1 | Novel Compounds and Pharmaceutical Preparations | DICOT AB (SE) | 2022-06-16 | — | — | US | claimed |
| EP-2807170-B1 | PHRAGMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | DICOT AB (SE) | 2019-03-13 | — | — | EP | claimed |
| EP-2162145-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL PREPARATIONS FROM NEOBEGUEA SPEC | DICOTYLEDON AB (SE) | 2016-05-04 | — | — | EP | claimed |
| US-20150011616-A1 | PHRAGAMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | DICOT PHARMA AB (SE) | 2015-01-08 | — | — | US | claimed |
| CN-104254537-A | Phragmalin limonoids for the treatment of sexual dysfunction | DICOTYLEDON AB | 2014-12-31 | — | — | CN | claimed |
| EP-2807170-A2 | PHRAGAMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | Dicotyledon AB (SE) | 2014-12-03 | — | — | EP | claimed |
| WO-2013110744-A2 | NOVEL COMPOUNDS, THEIR MANUFACTURE AND USES (II) | DICOTYLEDON AB (SE) | 2013-08-01 | — | — | WO | claimed |
| US-20100247593-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL PREPARATIONS | DICOTYLEDON AB (SE) | 2010-09-30 | — | — | US | claimed |
| EP-2162145-A2 | NOVEL COMPOUNDS AND PHARMACEUTICAL PREPARATIONS FROM NEOBEGUEA SPEC | Dicotyledon AB (SE) | 2010-03-17 | — | — | EP | claimed |
| WO-2008145996-A2 | NOVEL COMPOUNDS AND PHARMACEUTICAL PREPARATIONS | DICOTYLEDON AB (SE) | 2008-12-04 | — | — | WO | claimed |
| EP-0772597-B1 | 3,4-SUBSTITUTED PYRAZOLES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2001-12-12 | — | — | EP | claimed |
| EP-1127878-A1 | 3,4 - substituted pyrazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2001047896-A1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND THE USE THEREOF AS ANTITHROMBOTIC | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-05 | — | — | WO | claimed |
| US-20010006977-A1 | Benzimidazoles with antithrombotic activity | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2001-07-05 | — | — | US | claimed |
| US-6187504-B1 | PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION | JSR CORPORATION (JP) | 2001-02-13 | — | — | US | claimed |
| US-6028072-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 2000-02-22 | — | — | US | claimed |
| EP-0772597-A1 | 3,4-SUBSTITUTED PYRAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | claimed |
| WO-1996003385-A1 | 3,4-SUBSTITUTED PYRAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | claimed |
| US-5486534-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-01-23 | — | — | US | claimed |
| US-3933800-A | O-SUBSTITUTED OXIMES, MICROBIOCIDES | GRUPPO LEPETIT S.P.A. (IT) | 1976-01-20 | — | — | US | claimed |