Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540806 | 1.00 | TSHR (0.48) | TSHRALDH1A1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL15842868 | 0.91 | TSHR (0.42) | TSHRALDH1A1TDP1SMN1; SMN2MAPT | |
| SCHEMBL3999436 | 0.91 | TSHR (0.42) | TSHRALDH1A1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL15843265 | 0.91 | TSHR (0.42) | TSHRALDH1A1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL15843266 | 0.91 | TSHR (0.42) | TSHRALDH1A1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL15842869 | 0.91 | TSHR (0.42) | TSHRALDH1A1TDP1SMN1; SMN2MAPT | |
| SCHEMBL15843226 | 0.89 | TSHR (0.41) | TSHRALDH1A1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL15843227 | 0.89 | TSHR (0.41) | TSHRALDH1A1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL15843923 | 0.87 | TSHR (0.39) | TSHRALDH1A1TDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL15843922 | 0.87 | TSHR (0.39) | TSHRALDH1A1TDP1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315599-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2016-04-19 | — | — | US | claimed |
| US-20140323727-A1 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2014-10-30 | — | — | US | claimed |
| WO-2014107447-A1 | FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2014-07-10 | — | — | WO | claimed |
| US-20140187712-A1 | FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | claimed |
| US-20130150577-A1 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2013-06-13 | — | — | US | claimed |
| EP-2560939-A2 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | Actavis Group Ptc Ehf (IS) | 2013-02-27 | — | — | EP | claimed |
| WO-2011132083-A2 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2011-10-27 | — | — | WO | claimed |
| CN-1262616-C | Electronic device discharge coating and preparation method thereof | BEIJING ATOM HIGH TECH APPLIC (CN) | 2006-07-05 | — | — | CN | claimed |
| CN-1632008-A | Electronic device discharge coating and preparation method thereof | BEIJING ATOM HIGHTECH CO LTD (CN) | 2005-06-29 | — | — | CN | claimed |
| US-6608216-B2 | Preparing biaryl atropisomers; chirality transfer from stereogenic center of secondary alcohol to biaryl stereogenic axis via regioselective intramolecular migration | ABBOTT LABORATORIES | 2003-08-19 | — | — | US | claimed |
| US-20030073844-A1 | Process for the preparation of chiral glucocorticoid receptor agents | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | claimed |
| WO-2003002548-A1 | A PROCESS FOR THE PREPARATION OF CHIRAL GLUCOCORTICOID RECEPTOR AGENTS | ABBOTT LABORATORIES (US) | 2003-01-09 | — | — | WO | claimed |
| CN-116583286-A | Tetrahydrothienopyrimidine sulfonamide compounds | 某久拉斯株式会社 | 2023-08-11 | — | — | CN | disclosed |
| CN-111183142-B | Boric acid derivatives | 默克专利股份公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-114891070-A | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2022138812-A1 | TETRAHYDRO THIENOPYRIDINE SULFONAMIDE COMPOUND | モジュラス株式会社 | 2022-06-30 | — | — | WO | disclosed |
| WO-2003000646-A1 | SUBSTITUTED AROMATIC ETHERS AS INHIBITORS OF GLYCINE TRANSPORT | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| EP-0581618-B1 | Rubber composition and production thereof | SUMITOMO CHEMICAL CO (JP) | 1997-06-18 | — | — | EP | disclosed |
| US-5362794-A | Butadiene-styrene rubber, azodocarboxylic ester; automobile tires | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0581618-A1 | Rubber composition and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073844-A1 | Process for the preparation of chiral glucocorticoid receptor agents | NR3C1, NR3C2, MC2R | TSHR 210/4885ALDH1A1 3217/4885TDP1 4823/4885 |
| US-20140323727-A1 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | THPO, P2RY4, TPMT | TSHR 1050/4885ALDH1A1 2075/4885TDP1 768/4885 |
| US-20130150577-A1 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | THPO, P2RY4, TPMT | TSHR 1050/4885ALDH1A1 2075/4885TDP1 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.