SCHEMBL1269010

SCHEMBL1269010

O=C1OCCCCOC(=O)c2ccccc2-c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.48
MAOB P27338 3/20 0.48
ALOX15 P16050 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
POLB P06746 2/20 0.43
KDM4E B2RXH2 2/20 0.43
CES1 P23141 2/20 0.43
S100A4 P26447 2/20 0.43
CES2 O00748 1/20 0.43
APAF1 O14727 1/20 0.43
TERT O14746 1/20 0.43
NPC1 O15118 1/20 0.43
PLIN1 O60240 1/20 0.43
TDP2 O95551 1/20 0.43
S1PR4 O95977 1/20 0.43
LMNA P02545 1/20 0.43
PLA2G1B P04054 1/20 0.43
BCHE P06276 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29462577 0.97 MAOA (0.50) MAOAMAOBALOX15TDP1MEN1
SCHEMBL5709796 0.97 MAOA (0.50) MAOAMAOBALOX15TDP1MEN1
SCHEMBL24434352 0.97 MAOA (0.50) MAOAMAOBALOX15TDP1MEN1
SCHEMBL31106387 0.95 MAOA (0.48) MAOAMAOBALOX15TDP1MEN1
SCHEMBL1395558 0.95 MAOA (0.48) MAOAMAOBALOX15TDP1MEN1
SCHEMBL31680075 0.95 MAOA (0.48) MAOAMAOBALOX15TDP1MEN1
SCHEMBL24434346 0.95 MAOA (0.48) MAOAMAOBALOX15TDP1MEN1
SCHEMBL17672312 0.95 MAOA (0.48) MAOAMAOBALOX15TDP1MEN1
SCHEMBL2360787 0.95 MAOA (0.48) MAOAMAOBALOX15TDP1MEN1
SCHEMBL30043733 0.95 MAOA (0.48) MAOAMAOBALOX15TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3846655-B1 A SHOE COMPRISING A SOLE OF A THERMOPLASTIC MATERIAL AND A METHOD FOR USE IN MANUFACTURING SUCH A SHOE COVESTRO NETHERLANDS BV (NL) 2023-10-04 EP claimed
US-20210330025-A1 SHOE COMPRISING A SOLE OF A THERMOPLASTIC MATERIAL AND A METHOD FOR USE IN MANUFACTURING SUCH A SHOE COVESTRO (NETHERLANDS) B.V. (NL) 2021-10-28 US claimed
EP-3898795-A1 FOAMED COMPOSITION DSM IP Assets B.V. (NL) 2021-10-27 EP claimed
EP-3846655-A1 A SHOE COMPRISING A SOLE OF A THERMOPLASTIC MATERIAL AND A METHOD FOR USE IN MANUFACTURING SUCH A SHOE DSM IP Assets B.V. (NL) 2021-07-14 EP claimed
WO-2020127753-A1 FOAMED COMPOSITION DSM IP ASSETS B.V. (NL) 2020-06-25 WO claimed
WO-2018134166-A1 FOAMED COMPOSITION DSM INTELLECTUAL PROPERTY (NL) 2018-07-26 WO claimed
US-6855423-B2 Wrapped cord CONTINENTAL AG (DE) 2005-02-15 US claimed
WO-2024134119-A1 COMPOSITE COMPRISING AN ELASTOMER COMPRISING RUBBER PARTICLES AND A FOAM LAYER ARKEMA FRANCE (FR) 2024-06-27 WO disclosed
WO-2024009038-A1 ELASTOMER COMPOSITE COMPRISING PARTICLES OF CROSSLINKED RUBBER ARKEMA FRANCE (FR) 2024-01-11 WO disclosed
EP-3846655-B1 A SHOE COMPRISING A SOLE OF A THERMOPLASTIC MATERIAL AND A METHOD FOR USE IN MANUFACTURING SUCH A SHOE COVESTRO NETHERLANDS BV (NL) 2023-10-04 EP disclosed
WO-2023118760-A1 COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER AND A CROSSLINKED RUBBER POWDER ARKEMA FRANCE (FR) 2023-06-29 WO disclosed
US-20220048244-A1 POLYESTER POWDERS AND THE USE THEREOF IN THREE-DIMENSIONAL PRINTING PROCESSES STRATASYS INC. 2022-02-17 US disclosed
US-20210330025-A1 SHOE COMPRISING A SOLE OF A THERMOPLASTIC MATERIAL AND A METHOD FOR USE IN MANUFACTURING SUCH A SHOE COVESTRO (NETHERLANDS) B.V. (NL) 2021-10-28 US disclosed
WO-2020127757-A1 FOAM DSM IP ASSETS B.V. (NL) 2020-06-25 WO disclosed
WO-2020127753-A1 FOAMED COMPOSITION DSM IP ASSETS B.V. (NL) 2020-06-25 WO disclosed
WO-2020099304-A1 FOAMED COMPOSITION DSM IP ASSETS B.V. (NL) 2020-05-22 WO disclosed
WO-2018134166-A1 FOAMED COMPOSITION DSM INTELLECTUAL PROPERTY (NL) 2018-07-26 WO disclosed
EP-2459152-A2 ORAL CARE ARTICLE The Procter & Gamble Company (US) 2012-06-06 EP disclosed
US-20110027328-A1 Oral Care Articles and Methods THE PROCTER & GAMBLE COMPANY 2011-02-03 US disclosed
WO-2011014401-A2 ORAL CARE ARTICLES AND METHODS THE PROCTER & GAMBLE COMPANY (US) 2011-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110027328-A1 Oral Care Articles and Methods STOM, DSC1, DSG1 MAOA 4751/4885MAOB 4860/4885ALOX15 2001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.