Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268207 | 0.87 | — | — | |
| SCHEMBL6387867 | 0.84 | TSHR (0.35) | TSHRFAAH | |
| SCHEMBL1268937 | 0.81 | — | — | |
| SCHEMBL6387032 | 0.80 | CES2 (0.34) | TSHR | |
| SCHEMBL213566 | 0.80 | — | — | |
| SCHEMBL1268663 | 0.77 | CES2 (0.36) | TSHR | |
| SCHEMBL6388172 | 0.76 | CES2 (0.34) | TSHR | |
| SCHEMBL6389566 | 0.73 | CES2 (0.32) | TSHR | |
| SCHEMBL6387776 | 0.71 | LMNA (0.32) | — | |
| SCHEMBL1269319 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444740-B1 | SILICONES; ADHESIVES, SEALS | LOCTITE CORPORATION | 2002-09-03 | — | — | US | claimed |
| US-6413354-B1 | A SILANOL TERMINATED POLYSILOXANE FLUID, PLASTICIZER, FILLER AND CROSSLINKER THAT MAINTAINS ADHESION TO METALS; SEALS FOR USE IN AUTOMOBILES | LOCTITE CORPORATION | 2002-07-02 | — | — | US | claimed |
| US-8609797-B2 | Room temperature vulcanizable polymers | HONEYWELL INTERNATIONAL INC. (US) | 2013-12-17 | — | — | US | disclosed |
| US-20110028639-A1 | ROOM TEMPERATURE VULCANIZABLE POLYMERS | HONEYWELL INTERNATIONAL, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| US-20100225069-A1 | OIL RESISTANT RTV SILICONE | ILLINOIS TOOL WORKS, INC. | 2010-09-09 | — | — | US | disclosed |
| US-20070178321-A1 | CURABLE SILICONE COATING | ILLINOIS TOOL WORKS, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| US-7205050-B2 | Low shear adhesion RTV silicone | PERMATEX, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20050059835-A1 | Methods of refining silane compounds | HONEYWELL INTERNATIONAL INC. (US) | 2005-03-17 | — | — | US | disclosed |
| US-20050020754-A1 | Low shear adhesion RTV silicone | PERMATEX, INC. | 2005-01-27 | — | — | US | disclosed |
| US-6645339-B1 | Fluid resistant silicone compositions for sealing magnesium alloy components | HENKEL LOCTITE CORPORATION | 2003-11-11 | — | — | US | disclosed |
| US-6444740-B1 | SILICONES; ADHESIVES, SEALS | LOCTITE CORPORATION | 2002-09-03 | — | — | US | disclosed |
| US-6413354-B1 | A SILANOL TERMINATED POLYSILOXANE FLUID, PLASTICIZER, FILLER AND CROSSLINKER THAT MAINTAINS ADHESION TO METALS; SEALS FOR USE IN AUTOMOBILES | LOCTITE CORPORATION | 2002-07-02 | — | — | US | disclosed |
| US-5534588-A | STORAGE STABLE IN ONE-PACKAGE | ALLIEDSIGNAL INC. (US) | 1996-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059835-A1 | Methods of refining silane compounds | HDAC10, HDAC1, HDAC11 | TSHR 3353/4885FAAH 3227/4885 |
| US-20110028639-A1 | ROOM TEMPERATURE VULCANIZABLE POLYMERS | TET3, KDM3A, TET1 | TSHR 4581/4885FAAH 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.