Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572105 | 0.85 | SLC6A2 (0.64) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL28548162 | 0.80 | SLC6A2 (0.58) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL19118092 | 0.79 | SLC6A2 (0.52) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL4352224 | 0.78 | SLC6A2 (0.56) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL4674456 | 0.76 | TAAR1 (0.60) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL11310649 | 0.76 | SLC6A2 (0.54) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL3461269 | 0.76 | SLC6A2 (0.54) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL22296342 | 0.76 | SLC6A2 (0.54) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL113690 | 0.76 | SLC6A2 (0.54) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL3610318 | 0.76 | SLC6A2 (0.54) | SLC6A2TAAR1LMNACYP2D6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110691763-A | Method for preparing branched chain skip diene | 南方科技大学 | 2020-01-14 | — | — | CN | disclosed |
| US-8470844-B2 | Imidazoacridinone derivative compounds and methods for their use | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2013-06-25 | — | — | US | disclosed |
| US-8383873-B2 | Terminal 1,1-disubstituted alkenes, method of making and using thereof | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2013-02-26 | — | — | US | disclosed |
| EP-2155747-B1 | IMIDAZOL (1,2-A)PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS | GE HEALTHCARE LTD (GB) | 2012-10-24 | — | — | EP | disclosed |
| US-20110201840-A1 | TERMINAL 1,1-DISUBSTITUTED ALKENES, METHOD OF MAKING AND USING THEREOF | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2011-08-18 | — | — | US | disclosed |
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |
| US-20110028507-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-02-03 | — | — | US | disclosed |
| WO-2010118575-A1 | RACEMIC ENANTIOMERS RESOLUTING | CHENGDU ORGANIC CHEMICALS CO., LTD, CHINESE ACADEMY OF SCIENCE (CN) | 2010-10-21 | — | — | WO | disclosed |
| US-20100137351-A1 | Imidazoacridinone derivative compounds and methods for their use | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| EP-2188295-A2 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | Crystalgenomics, Inc. (KR) | 2010-05-26 | — | — | EP | disclosed |
| US-6143895-A | TETRAHYDROQUINOLINONE COMPOUND | TREGA BIOSCIENCES, INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6107458-A | FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0983507-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | Trega Biosciences, Inc. (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0977989-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 2000-02-09 | — | — | EP | disclosed |
| US-5925527-A | SCREENING NEW PHARMACEUTICALS | TREGA BIOSCIENCES, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| US-5840500-A | OPIOD RECEPTORS AS ANALGESICS AND CENTRALLY ACTING PAIN KILLERS | TREGA BIOSCIENCES, INC. (US) | 1998-11-24 | — | — | US | disclosed |
| WO-1998034111-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996011210-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137351-A1 | Imidazoacridinone derivative compounds and methods for their use | IDH3A, IDH3B, ABL1 | SLC6A2 3806/4885TAAR1 2919/4885LMNA 499/4885 |
| US-20110028507-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | EGLN3, EGLN2, HIF1A | SLC6A2 2427/4885TAAR1 4160/4885LMNA 3768/4885 |
| US-20110201840-A1 | TERMINAL 1,1-DISUBSTITUTED ALKENES, METHOD OF MAKING AND USING THEREOF | ALKBH1, ALK, ALKBH3 | SLC6A2 2908/4885TAAR1 418/4885LMNA 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.