Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635558 | 0.97 | — | — | |
| SCHEMBL8718542 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL23174550 | 0.88 | — | — | |
| SCHEMBL4231793 | 0.85 | HRH3 (0.32) | — | |
| SCHEMBL3985738 | 0.84 | — | — | |
| SCHEMBL4720625 | 0.81 | — | — | |
| SCHEMBL4721344 | 0.81 | L3MBTL1 (0.34) | MEN1KMT2A | |
| SCHEMBL1206197 | 0.78 | HRH3 (0.33) | MEN1KMT2A | |
| SCHEMBL4765150 | 0.78 | L3MBTL1 (0.32) | MEN1KMT2A | |
| SCHEMBL16099104 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234284-A1 | Pyrazolo[1,5-a]Pyrimidin-7-Yl Amine Derivatives as Protein Kinase Inhibitors | NOVARTIS AG (CH) | 2008-09-25 | — | — | US | claimed |
| EP-1910368-A1 | PYRAZOLO[1.5-A]PYRIMIDIN-7-YL AMINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | Novartis AG (CH) | 2008-04-16 | — | — | EP | claimed |
| EP-1765877-A4 | RADIATION-CURABLE COATINGS FOR WOOD SUBSTRATES FROM MULTIFUNCTIONAL ACRYLATE OLIGOMERS | ASHLAND LICENSING & INTELLECTU (US) | 2007-08-29 | — | — | EP | claimed |
| EP-1765877-A2 | RADIATION-CURABLE COATINGS FOR WOOD SUBSTRATES FROM MULTIFUNCTIONAL ACRYLATE OLIGOMERS | Ashland Licensing and Intellectual Property LLC (US) | 2007-03-28 | — | — | EP | claimed |
| WO-2007009773-A1 | PYRAZOLO[1.5-A]PYRIMIDIN-7-YL AMINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2007-01-25 | — | — | WO | claimed |
| WO-2005111105-A2 | RADIATION-CURABLE COATINGS FOR WOOD SUBSTRATES FROM MULTIFUNCTIONAL ACRYLATE OLIGOMERS | ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) | 2005-11-24 | — | — | WO | claimed |
| US-20050245636-A1 | Radiation-curable coatings for wood substrates from multifunctional acrylate oligomers | ASHLAND INC. (US) | 2005-11-03 | — | — | US | claimed |
| JP-63057585-A | — | — | None | — | — | JP | disclosed |
| US-10258603-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| EP-1329975-B1 | NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY CELL AND NON-AQUEOUS LIQUID ELECTROLYTE ELECTRIC DOUBLE LAYER CAPACITOR | BRIDGESTONE CORP (JP) | 2018-04-25 | — | — | EP | disclosed |
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
| EP-3218376-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | Genentech, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2927228-B1 | Novel physiologically active substances | EISAI R&D MAN CO LTD (JP) | 2016-09-07 | — | — | EP | disclosed |
| US-20060009439-A1 | Novel physiologically active substances | MERCIAN CORPORATION (JP) | 2006-01-12 | — | — | US | disclosed |
| US-20050245514-A1 | Novel physiologically active substances | MICROBIOPHARM JAPAN CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| EP-1548121-A1 | NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCES | MERCIAN CORPORATION (JP) | 2005-06-29 | — | — | EP | disclosed |
| EP-1541570-A1 | NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCE | MERCIAN CORPORATION (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1508570-A1 | NOVEL PHYSIOLGICALLY ACTIVE SUBSTANCES | MERCIAN CORPORATION (JP) | 2005-02-23 | — | — | EP | disclosed |
| WO-1995015955-A1 | 2,4-DIAMINOTHIAZOLES AND THEIR PRODUCTION | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-15 | — | — | WO | disclosed |
| JP-S6357585-A | ISOQUINOLINE DERIVATIVE | MITSUI TOATSU CHEM INC | 1988-03-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245514-A1 | Novel physiologically active substances | HIF1A, HIF1AN, VEGFA | KDM4E 4239/4885MEN1 2091/4885ALDH1A1 133/4885 |
| US-20060009439-A1 | Novel physiologically active substances | HIF1A, HIF1AN, VEGFA | KDM4E 3533/4885MEN1 2851/4885ALDH1A1 108/4885 |
| US-20080234284-A1 | Pyrazolo[1,5-a]Pyrimidin-7-Yl Amine Derivatives as Protein Kinase Inhibitors | MAP3K5, MAP3K20, MAP3K7 | KDM4E 1865/4885MEN1 2127/4885ALDH1A1 2533/4885 |
| US-10258603-B2 | Therapeutic compounds and uses thereof | BRD4, BRDT, BRD3 | KDM4E 320/4885MEN1 1364/4885ALDH1A1 1563/4885 |
| US-20170340604-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRD3 | KDM4E 320/4885MEN1 1364/4885ALDH1A1 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.