Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12691840 | 0.78 | CYP3A4 (0.37) | CYP19A1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29422798 | 0.74 | CYP3A4 (0.43) | ALDH1A1LMNAPOLBTP53HTT | |
| SCHEMBL564939 | 0.74 | CYP3A4 (0.43) | ALDH1A1LMNAPOLBTP53HTT | |
| SCHEMBL4417199 | 0.67 | MAPT (0.42) | CYP19A1ALDH1A1LMNAPOLBHTT | |
| SCHEMBL8109589 | 0.62 | MTNR1A (0.45) | ALDH1A1LMNATP53CYP3A4CYP2D6 | |
| SCHEMBL7477677 | 0.62 | KMT2A (0.43) | ALDH1A1LMNAPOLBTP53HTT | |
| SCHEMBL8397407 | 0.62 | KMT2A (0.43) | ALDH1A1LMNAPOLBTP53HTT | |
| SCHEMBL4412748 | 0.61 | CYP19A1 (0.38) | CYP19A1ALDH1A1LMNAPOLBCYP3A4 | |
| SCHEMBL5000805 | 0.61 | CYP2D6 (0.65) | ALDH1A1LMNATP53HTTCYP3A4 | |
| SCHEMBL9144592 | 0.60 | GAA (0.41) | ALDH1A1LMNAPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120241250-A1 | Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers | EAKIN GEORGE R (US) | 2012-09-27 | — | — | US | disclosed |
| US-20120241250-A1 | Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers | EAKIN GEORGE R (US) | 2012-09-27 | — | — | US | disclosed |