Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 1.00 |
| ▸ | NPC1 | O15118 | 10/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | CASP3 | P42574 | 2/20 | 1.00 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 1.00 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 1.00 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 1.00 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.81 |
| ▸ | TUBB | P07437 | 5/20 | 0.81 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.81 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.81 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.81 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.81 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.81 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.81 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.81 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.81 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.81 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.81 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508835 | 0.90 | TUBB4A (1.00) | RAB9ANPC1KDM4ECASP3SENP8 | |
| SCHEMBL1508832 | 0.90 | TUBB4A (1.00) | RAB9ANPC1KDM4ECASP3SENP8 | |
| SCHEMBL12692460 | 0.86 | TUBB4A (0.81) | RAB9ANPC1KDM4ECASP3SENP8 | |
| SCHEMBL17890027 | 0.86 | TUBB4A (0.81) | RAB9ANPC1KDM4ECASP3SENP8 | |
| SCHEMBL17890029 | 0.86 | TUBB4A (0.81) | RAB9ANPC1KDM4ECASP3SENP8 | |
| SCHEMBL16448290 | 0.85 | TUBB4A (0.74) | RAB9ANPC1KDM4ECASP3SENP8 | |
| SCHEMBL17890024 | 0.85 | TUBB4A (0.77) | RAB9ANPC1KDM4ECASP3SENP8 | |
| SCHEMBL16448291 | 0.85 | TUBB4A (0.74) | RAB9ANPC1KDM4ECASP3SENP8 | |
| SCHEMBL17890026 | 0.85 | TUBB4A (0.77) | RAB9ANPC1KDM4ECASP3SENP8 | |
| SCHEMBL17890111 | 0.84 | TUBB4A (0.72) | RAB9ANPC1KDM4ECASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245166-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES, CAUSATION OF MEMORY ENHANCEMENT, AND ASSAY FOR SCREENING COMPOUNDS FOR SUCH | SOUTHERN RESEARCH INSTITUTE (US) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245166-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES, CAUSATION OF MEMORY ENHANCEMENT, AND ASSAY FOR SCREENING COMPOUNDS FOR SUCH | NFKBIA, NFRKB, TFEB | RAB9A 2402/4885NPC1 467/4885KDM4E 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.