Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14969125 | 0.88 | TPH1 (1.00) | TPH1 | |
| SCHEMBL308509 | 0.88 | TPH1 (1.00) | TPH1 | |
| SCHEMBL3408238 | 0.88 | TPH1 (1.00) | TPH1 | |
| SCHEMBL14969126 | 0.88 | TPH1 (1.00) | TPH1 | |
| SCHEMBL308510 | 0.88 | TPH1 (1.00) | TPH1 | |
| SCHEMBL870382 | 0.84 | TPH1 (0.76) | TPH1 | |
| SCHEMBL870383 | 0.84 | TPH1 (0.76) | TPH1 | |
| SCHEMBL28773704 | 0.82 | TPH1 (0.75) | TPH1 | |
| SCHEMBL3409703 | 0.79 | TPH1 (0.83) | TPH1 | |
| SCHEMBL307877 | 0.79 | TPH1 (0.83) | TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984344-B1 | MULTICYCLIC AMINO ACID DERIVATIVES AND METHODS OF THEIR USE | LEXICON PHARMACEUTICALS INC (US) | 2012-09-26 | — | — | EP | disclosed |