Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308510 | 0.86 | TPH1 (1.00) | TPH1 | |
| SCHEMBL308509 | 0.86 | TPH1 (1.00) | TPH1 | |
| SCHEMBL3408238 | 0.86 | TPH1 (1.00) | TPH1 | |
| SCHEMBL14969126 | 0.86 | TPH1 (1.00) | TPH1 | |
| SCHEMBL14969125 | 0.86 | TPH1 (1.00) | TPH1 | |
| SCHEMBL870382 | 0.86 | TPH1 (0.76) | TPH1 | |
| SCHEMBL870383 | 0.86 | TPH1 (0.76) | TPH1 | |
| SCHEMBL12694100 | 0.82 | TPH1 (0.78) | TPH1 | |
| SCHEMBL307877 | 0.79 | TPH1 (0.83) | TPH1 | |
| SCHEMBL3409703 | 0.79 | TPH1 (0.83) | TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351451-A | Polycyclic amino acid derivatives and methods of use thereof | LEXICON GENETICS INC (US) | 2009-01-21 | — | — | CN | claimed |