SCHEMBL1269481

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1269787	0.86	ALDH1A1 (0.40)	ALDH1A1L3MBTL1TSHRMEN1KMT2A
	SCHEMBL1269747	0.86	ALDH1A1 (0.42)	ALDH1A1L3MBTL1ATMTSHRMEN1
	SCHEMBL1269703	0.83	CCKBR (0.44)	ALDH1A1L3MBTL1ATMTSHRMEN1
	SCHEMBL1269584	0.83	ALDH1A1 (0.43)	ALDH1A1L3MBTL1ATMTSHRMEN1
	SCHEMBL1269926	0.83	ALDH1A1 (0.46)	ALDH1A1L3MBTL1ATMTSHRMEN1
	SCHEMBL12900226	0.82	GAA (0.41)	ALDH1A1L3MBTL1MEN1KMT2ALMNA
	SCHEMBL12900217	0.80	GAA (0.42)	ALDH1A1L3MBTL1LMNAGLAGAA
	SCHEMBL1268625	0.80	ALDH1A1 (0.39)	ALDH1A1L3MBTL1ATMTSHRMEN1
	SCHEMBL1268542	0.79	ALDH1A1 (0.42)	ALDH1A1L3MBTL1ATMTSHRMEN1
	SCHEMBL1269559	0.78	ALDH1A1 (0.38)	ALDH1A1L3MBTL1ATMTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.