Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 20/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2040048 | 0.99 | TPSAB1 (0.60) | TPSAB1CYP2C9CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL12543454 | 0.93 | TPSAB1 (0.56) | TPSAB1CYP2C9CYP2C19KCNH2 | |
| SCHEMBL12643122 | 0.92 | TPSAB1 (0.59) | TPSAB1CYP2C9CYP2C19KCNH2 | |
| SCHEMBL12643064 | 0.92 | TPSAB1 (0.60) | TPSAB1 | |
| SCHEMBL12695184 | 0.92 | TPSAB1 (0.50) | TPSAB1CYP2C9CYP2C19KCNH2 | |
| SCHEMBL12695198 | 0.91 | TPSAB1 (0.51) | TPSAB1CYP2C9CYP2C19KCNH2 | |
| SCHEMBL12642974 | 0.91 | TPSAB1 (0.60) | TPSAB1CYP2C9CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL2044380 | 0.91 | TPSAB1 (0.49) | TPSAB1CYP2C9CYP2C19KCNH2 | |
| SCHEMBL12695204 | 0.91 | TPSAB1 (0.52) | TPSAB1CYP2C9CYP2C19KCNH2 | |
| SCHEMBL12643130 | 0.91 | TPSAB1 (0.57) | TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245161-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2012-09-27 | — | — | US | disclosed |
| US-20120245161-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245161-A1 | INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | TPSAB1, TPSB2, TPSD1 | TPSAB1 1/4885CYP2C9 800/4885CYP2C19 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.