Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694336 | 0.93 | KDM4E (0.48) | HSD11B1RARBRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL18462105 | 0.85 | HSD11B1 (0.40) | HSD11B1RARBRAB9AKDM4ENISCH | |
| SCHEMBL18418545 | 0.82 | RARB (0.53) | HSD11B1RARBRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL21815406 | 0.81 | NISCH (0.35) | RAB9AKDM4ENISCHNPC1CA2 | |
| SCHEMBL21815405 | 0.81 | NISCH (0.35) | RAB9AKDM4ENISCHNPC1CA2 | |
| SCHEMBL17694326 | 0.81 | BDKRB2 (0.40) | HSD11B1RARBRAB9AKDM4EMAPT | |
| SCHEMBL22238940 | 0.80 | SKP2 (0.36) | HSD11B1RARBRAB9AKDM4ENISCH | |
| SCHEMBL12374382 | 0.80 | HSD11B1 (0.45) | HSD11B1RARBRAB9AKDM4ENISCH | |
| SCHEMBL16265324 | 0.78 | RARB (0.52) | HSD11B1RARBRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL17694334 | 0.76 | HSD11B1 (0.42) | HSD11B1RARBRAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012126570-A1 | COMPOSITIONS FOR A LIQUID CRYSTALLINE MEDIUM AND APPLICATION THEREOF IN HIGH FREQUENCY COMPONENTS | MERCK PATENT GMBH (DE) | 2012-09-27 | — | — | WO | disclosed |