SCHEMBL1269637

SCHEMBL1269637

C=Cc1ccc(OCCC[Si](C)(OCC)OCC)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 5/20 0.51
CHRNB4 P30926 4/20 0.51
CHRNA3 P32297 4/20 0.51
CHRNB2 P17787 3/20 0.51
CHRNA4 P43681 3/20 0.51
ALDH1A1 P00352 5/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
PTPN1 P18031 2/20 0.38
AHR P35869 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 3/20 0.36
CYP2D6 P10635 3/20 0.36
CYP1A2 P05177 2/20 0.36
TP53 P04637 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15505269 0.92 CHRNA7 (0.53) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL9314774 0.88 CHRNA7 (0.51) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL9183219 0.86 CHRNA7 (0.53) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL9460875 0.86 CHRNA7 (0.40) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL4372162 0.84 CHRNA7 (0.50) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL9315267 0.83 TLR4 (0.41) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL15505290 0.83 CHRNA7 (0.47) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL14369373 0.82 CHRNA7 (0.54) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL15505292 0.81 CHRNA7 (0.54) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL8759516 0.81 CHRNB2 (0.33) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0367219-B1 Polyorganosiloxane series thermoplastic resin and composition thereof JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-08-31 EP claimed
US-5147947-A Graft polymer containing vinyl monomer; friction resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-09-15 US claimed
EP-0367219-A2 Polyorganosiloxane series thermoplastic resin and composition thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-05-09 EP claimed
US-20250019536-A1 STRESS REDUCING AGENT AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2025-01-16 US disclosed
EP-4446352-A1 WATER-BASED COATING Kaneka Corporation (JP) 2024-10-16 EP disclosed
US-20240327671-A1 WATER-BASED COATING KANEKA CORPORATION (JP) 2024-10-03 US disclosed
CN-118369388-A Water paint 株式会社钟化 2024-07-19 CN disclosed
WO-2023190135-A1 STRESS REDUCING AGENT AND RESIN COMPOSITION 株式会社カネカ 2023-10-05 WO disclosed
WO-2023106317-A1 WATER-BASED COATING 株式会社カネカ 2023-06-15 WO disclosed
US-11046800-B2 Resin component disposed in route of beam emitted by radar device, radome, and radar device TECHNO-UMG CO., LTD. (JP) 2021-06-29 US disclosed
CN-108603005-B Resin member disposed on path of beam emitted from radar device, radome, and radar device 大科能宇菱通株式会社 2020-11-03 CN disclosed
EP-0710679-A2 Process for producing polyorganosiloxane-based thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-05-08 EP disclosed
US-5457167-A Impact strength, chemical resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-10-10 US disclosed
EP-0653447-A1 Polyorganosiloxane-type thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-05-17 EP disclosed
EP-0367219-B1 Polyorganosiloxane series thermoplastic resin and composition thereof JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-08-31 EP disclosed
US-5342983-A Polymer reforming agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-08-30 US disclosed
US-5210252-A 3-(VINYLPHENYLOXY)PROPYLSILANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-05-11 US disclosed
EP-0529583-A1 3-(Vinylphenyloxy) propylsilane compound Shin-Etsu Chemical Co., Ltd. (JP) 1993-03-03 EP disclosed
US-5147947-A Graft polymer containing vinyl monomer; friction resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-09-15 US disclosed
EP-0367219-A2 Polyorganosiloxane series thermoplastic resin and composition thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-05-09 EP disclosed