Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849436 | 0.88 | CA1 (0.34) | RAPGEF4KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL8972077 | 0.72 | CA1 (0.33) | RAPGEF4KMT2AMEN1ALDH1A1ALOX5 | |
| SCHEMBL4170912 | 0.66 | RAPGEF4 (0.50) | RAPGEF4KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL17973534 | 0.64 | CYP2C9 (0.42) | KMT2AMEN1POLBALOX5LMNA | |
| SCHEMBL21433771 | 0.61 | ALOX5 (0.32) | RAPGEF4KMT2AALDH1A1ALOX5GAA | |
| SCHEMBL1571319 | 0.60 | RAPGEF4 (0.47) | RAPGEF4KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL1156787 | 0.59 | ALOX5 (0.40) | ALDH1A1ALOX5ALKLMNAL3MBTL1 | |
| SCHEMBL18277611 | 0.58 | RAPGEF4 (0.55) | RAPGEF4ALDH1A1POLBALKLMNA | |
| SCHEMBL30877436 | 0.57 | RAPGEF4 (0.43) | RAPGEF4KMT2AALDH1A1ALKGAA | |
| SCHEMBL27559622 | 0.56 | SLC1A3 (0.41) | RAPGEF4POLBALOX5CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120244551-A1 | PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-09-27 | — | — | US | disclosed |