SCHEMBL12698229

SCHEMBL12698229

Cc1cccc2c1C=Cc1ccccc1N2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
GAA P10253 2/20 0.61
P2RX4 Q99571 1/20 0.38
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ACHE P22303 3/20 0.33
TSHR P16473 1/20 0.33
POLB P06746 2/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA7 P43166 1/20 0.32
HTR2C P28335 3/20 0.31
HTR5A P47898 1/20 0.31
BCHE P06276 2/20 0.30
CYP1A2 P05177 2/20 0.30
CYP2A6 P11509 2/20 0.30
ALOX5 P09917 1/20 0.30
CD44 P16070 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iminostilbene SCHEMBL75288 0.78 MAPT (1.00) MAPTGAAP2RX4RAB9ASMN1; SMN2
Iminostilbene SCHEMBL29926907 0.78 MAPT (1.00) MAPTGAAP2RX4RAB9ASMN1; SMN2
SCHEMBL16131316 0.78 MAPT (0.58) MAPTGAAP2RX4RAB9ASMN1; SMN2
SCHEMBL7743045 0.77 MAPT (0.61) MAPTGAAP2RX4RAB9ASMN1; SMN2
Iminostilbene SCHEMBL9685179 0.76 MAPT (0.94) MAPTGAAP2RX4RAB9ASMN1; SMN2
Iminostilbene SCHEMBL5063042 0.76 MAPT (0.94) MAPTGAAP2RX4RAB9ASMN1; SMN2
Water SCHEMBL9621535 0.76 MAPT (0.59) MAPTGAAP2RX4RAB9ASMN1; SMN2
SCHEMBL29672228 0.75 GAA (0.44) MAPTGAAP2RX4
SCHEMBL10043988 0.74 MAPT (0.52) MAPTGAAP2RX4RAB9ASMN1; SMN2
SCHEMBL11473457 0.73 MAPT (0.55) MAPTGAAP2RX4RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2502926-A1 COMPOUND Panasonic Corporation (JP) 2012-09-26 EP disclosed