Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17072898 | 0.78 | MAPT (0.58) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| Iminostilbene SCHEMBL75288 | 0.78 | MAPT (1.00) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| Iminostilbene SCHEMBL29926907 | 0.78 | MAPT (1.00) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| SCHEMBL12698229 | 0.77 | MAPT (0.61) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| Iminostilbene SCHEMBL9685179 | 0.76 | MAPT (0.94) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| Iminostilbene SCHEMBL5063042 | 0.76 | MAPT (0.94) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| Water SCHEMBL9621535 | 0.76 | MAPT (0.59) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| SCHEMBL3971126 | 0.74 | — | — | |
| SCHEMBL11473457 | 0.73 | MAPT (0.55) | MAPTGAAP2RX4RAB9ASMN1; SMN2 | |
| SCHEMBL29672228 | 0.72 | GAA (0.44) | MAPTGAAP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476221-B1 | Tribenzazepine compound and production method thereof | FUJI PHOTO FILM CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |