Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828994 | 0.83 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL4661109 | 0.82 | — | — | |
| SCHEMBL2932038 | 0.81 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL11503365 | 0.81 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL1196043 | 0.76 | SLC1A3 (0.65) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL606620 | 0.76 | SLC1A3 (0.65) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL10591110 | 0.76 | SLC1A3 (0.65) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL1197330 | 0.76 | SLC1A3 (0.65) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL24687333 | 0.76 | TSHR (0.36) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2933990 | 0.76 | PDE4A (0.54) | SLC1A3SLC1A2SLC1A1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012106190-A1 | C-17 AND C-3 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-08-09 | — | — | WO | disclosed |