Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.65 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.65 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1196043 | 1.00 | SLC1A3 (0.65) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL10591110 | 1.00 | SLC1A3 (0.65) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL606620 | 1.00 | SLC1A3 (0.65) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL9885923 | 0.86 | SLC1A3 (0.52) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL2878257 | 0.86 | SLC1A3 (0.52) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL13304410 | 0.84 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1TP53MMP1 | |
| SCHEMBL1085084 | 0.84 | — | — | |
| SCHEMBL466551 | 0.84 | — | — | |
| SCHEMBL15114574 | 0.84 | — | — | |
| SCHEMBL6548114 | 0.84 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693704-B1 | Semi-organic crystals for nonlinear optical devices | ROCKWELL INTERNATIONAL CORP (US) | 2002-08-28 | — | — | EP | claimed |
| EP-3976692-A1 | AQUEOUS DISPERSIONS OF PRE-CROSSLINKED ORGANOPOLYSILOXANES | Wacker Chemie AG (DE) | 2022-04-06 | — | — | EP | disclosed |
| WO-2020239229-A1 | AQUEOUS DISPERSIONS OF PRE-CROSSLINKED ORGANOPOLYSILOXANES | WACKER CHEMIE AG (DE) | 2020-12-03 | — | — | WO | disclosed |
| US-20170342027-A1 | CHIRAL RESOLUTION METHOD OF N-[4-(1-AMINOETHYL)-PHENYL]-SULFONAMIDE DERIVATIVES | AMOREPACIFIC CORPORATION (KR) | 2017-11-30 | — | — | US | disclosed |
| US-9782746-B2 | Polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160114309-A1 | Polymeric Ionic Liquids, Methods of Making and Methods of Use Thereof | THE UNIVERSITY OF TOLEDO (US) | 2016-04-28 | — | — | US | disclosed |
| US-9249261-B2 | Polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2016-02-02 | — | — | US | disclosed |
| US-8956445-B2 | High stability diionic liquid salts | SIGMA-ALDRICH CO. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8759583-B2 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | TEVA SANTE (FR) | 2014-06-24 | — | — | US | disclosed |
| US-8734673-B2 | Boron selective ionic liquids and polymeric ionic liquids, methods of making and methods of use thereof | THE UNIVERSITY OF TOLEDO (US) | 2014-05-27 | — | — | US | disclosed |
| US-20050222257-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CEPHALON, INC. (US) | 2005-10-06 | — | — | US | disclosed |
| US-20050080256-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | TEVA SANTE (FR) | 2005-04-14 | — | — | US | disclosed |
| WO-2005028428-A1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2005-03-31 | — | — | WO | disclosed |
| EP-1516869-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CEPHALON FRANCE (FR) | 2005-03-23 | — | — | EP | disclosed |
| US-5581010-A | Semi-organic crystals for nonlinear optical devices | ROCKWELL INTERNATIONAL CORPORATION (US) | 1996-12-03 | — | — | US | disclosed |
| US-5510470-A | CONTAINS A DIDEOXYSACCHARIDE; USED WITH ZERO VALENT NICKEL AS A CATALYST FOR ENANTIOSELECTIVE HYDROCYANATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| US-5484902-A | HYDROCYANATION OF VINYL AROMATICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| US-5312957-A | 2-/6-Methoxy-2-naphthalene/propionitrile | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5175335-A | Reacting vinyl aryl compounds with a source of hydrocyanic acid in presence of nickle zero valent compound and nonracemic bidentate organophosphorus ligand | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-4942227-A | ANTITUMOR AGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1990-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222257-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CYP2F1, SULT1A1, SULT2A1 | SLC1A3 1079/4885SLC1A2 497/4885SLC1A1 756/4885 |
| US-20170342027-A1 | CHIRAL RESOLUTION METHOD OF N-[4-(1-AMINOETHYL)-PHENYL]-SULFONAMIDE DERIVATIVES | DHCR24, SRR, ACMSD | SLC1A3 2297/4885SLC1A2 1546/4885SLC1A1 1796/4885 |
| US-20050080256-A1 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | MAOA, CYP2F1, MAOB | SLC1A3 1115/4885SLC1A2 493/4885SLC1A1 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.