Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503365 | 1.00 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1PDE4ATSHR | |
| SCHEMBL20828994 | 0.88 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1PDE4ATSHR | |
| SCHEMBL722389 | 0.82 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1PDE4ATSHR | |
| SCHEMBL7290471 | 0.82 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1PDE4ATSHR | |
| SCHEMBL7291825 | 0.82 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1PDE4ATSHR | |
| SCHEMBL20986908 | 0.82 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1PDE4ATSHR | |
| SCHEMBL12610770 | 0.82 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1PDE4ATSHR | |
| SCHEMBL12698338 | 0.81 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL14892561 | 0.78 | PDE4A (0.44) | SLC1A3SLC1A2SLC1A1PDE4ATSHR | |
| SCHEMBL12776176 | 0.78 | PDE4A (0.44) | SLC1A3SLC1A2SLC1A1PDE4ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |