SCHEMBL126985

SCHEMBL126985

CCNS(=O)(=O)c1ccc(C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
CYP2C9 P11712 1/20 0.61
CA12 O43570 2/20 0.59
CA9 Q16790 2/20 0.59
GBA1 P04062 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
ATM Q13315 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
GAA P10253 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CYP19A1 P11511 1/20 0.58
TSHR P16473 1/20 0.58
CA2 P00918 2/20 0.57
CA1 P00915 1/20 0.57
MMP1 P03956 1/20 0.57
MMP2 P08253 1/20 0.57
MMP9 P14780 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29165439 0.98 ALDH1A1 (0.96) ALDH1A1MEN1KMT2ACYP2C9CA12
SCHEMBL28678471 0.98 ALDH1A1 (0.96) ALDH1A1MEN1KMT2ACYP2C9CA12
SCHEMBL11511836 0.91 ALDH1A1 (0.83) ALDH1A1KMT2ACYP2C9CA12CA9
P-Toluenesulfonamide SCHEMBL15517091 0.91 ALDH1A1 (0.82) ALDH1A1MEN1KMT2ACYP2C9CA12
Oxirane SCHEMBL8657873 0.91 ALDH1A1 (0.82) ALDH1A1MEN1KMT2ACYP2C9CA12
SCHEMBL27637625 0.85 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ACYP2C9CA12
P-Toluenesulfonamide SCHEMBL8608429 0.85 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL5567042 0.84 ALDH1A1 (0.75) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL634316 0.83 ALDH1A1 (0.71) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL11771962 0.83 ALDH1A1 (0.70) ALDH1A1MEN1KMT2ACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3072 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745119-A1 ISOCYANATE COMPOSITION Hanwha Solutions Corporation (KR) 2026-05-20 EP claimed
US-20260041654-A1 METHOD FOR PREVENTING OR TREATING INFLAMMATORY SKIN DISEASE GONGWIN BIOPHARM CO., LTD (TW) 2026-02-12 US claimed
US-12409158-B2 Combination therapy for treating cancer GONGWIN BIOPHARM CO., LTD (TW) 2025-09-09 US claimed
US-12390971-B2 Process and system for blending a plasticizer with a polysaccharide ester polymer CELANESE INTERNATIONAL CORPORATION (US) 2025-08-19 US claimed
EP-4574144-A1 METHOD FOR TREATING PERIPHERAL NERVE SHEATH TUMOR Gongwin Biopharm Co., Ltd. (TW) 2025-06-25 EP claimed
CN-120059610-A Co-extrusion photovoltaic adhesive film composition, co-extrusion adhesive film, and preparation method and application thereof 中国石油化工股份有限公司 2025-05-30 CN claimed
EP-4558557-A1 COMPOSITION CONTAINING CELLULOSE ESTER POLYMER WITH ENHANCED MELT STRENGTH AGENT Celanese International Corporation (US) 2025-05-28 EP claimed
CN-120005536-A Polyvinyl butyral composition and preparation method and application thereof 中国石油化工股份有限公司 2025-05-16 CN claimed
CN-120005339-A Luminous polyvinyl butyral composition and preparation method and application thereof 中国石油化工股份有限公司 2025-05-16 CN claimed
CN-119894971-A Compositions containing cellulose ester polymers and enhanced melt strength agents 国际人造丝公司 2025-04-25 CN claimed
US-4363866-A SULFONE OR SULFONAMIDE VEHICLE BEDFORD LIMITED (GB) 1982-12-14 US claimed
US-4297260-A Erasable writing medium composition LIQUID PAPER CORPORATION (US) 1981-10-27 US claimed
US-4240832-A CALCIUM HYDROXIDE WITH CONDENSATE OF A SALICYLATE ESTER AND AN ALDEHYDE SYBRON CORPORATION (US) 1980-12-23 US claimed
EP-0012521-A2 Vesicular recording materials and process for their production BEXFORD LIMITED (GB) 1980-06-25 EP claimed
US-4141869-A COPOLYAMIDE, HYDROPHOBIC SILICONE PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1979-02-27 US claimed
US-4093492-A HEAT SEALING PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-06-06 US claimed
US-4030957-A HEAT SEALING PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-06-21 US claimed
US-4014847-A SULFONATED ADDITION POLYMERS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-03-29 US claimed
US-3950297-A HEAT-SEALING AGENTS PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-04-13 US claimed
US-3948844-A HEAT SEALANTS PLATE BONN GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-04-06 US claimed