SCHEMBL28678471

SCHEMBL28678471

CCNS(=O)(=O)c1ccc(C)cc1.[KH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.96
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
CYP2C9 P11712 1/20 0.59
CA12 O43570 2/20 0.58
CA9 Q16790 2/20 0.58
GBA1 P04062 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
ATM Q13315 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
GAA P10253 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CYP19A1 P11511 1/20 0.56
TSHR P16473 1/20 0.56
CA2 P00918 2/20 0.55
CA1 P00915 1/20 0.55
MMP1 P03956 1/20 0.55
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126985 0.98 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ACYP2C9CA12
SCHEMBL29165439 0.96 ALDH1A1 (0.96) ALDH1A1MEN1KMT2ACYP2C9CA12
SCHEMBL11511836 0.89 ALDH1A1 (0.83) ALDH1A1KMT2ACYP2C9CA12CA9
P-Toluenesulfonamide SCHEMBL15517091 0.89 ALDH1A1 (0.82) ALDH1A1MEN1KMT2ACYP2C9CA12
Oxirane SCHEMBL8657873 0.89 ALDH1A1 (0.82) ALDH1A1MEN1KMT2ACYP2C9CA12
SCHEMBL27637625 0.83 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ACYP2C9CA12
P-Toluenesulfonamide SCHEMBL8608429 0.83 ALDH1A1 (0.72) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL5567042 0.83 ALDH1A1 (0.75) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL634316 0.82 ALDH1A1 (0.71) ALDH1A1MEN1KMT2ACA12CA9
SCHEMBL11771962 0.81 ALDH1A1 (0.70) ALDH1A1MEN1KMT2ACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754509-A Method for preparing conjugated diene with single stereo configuration from allyl alcohol compound 中山大学 2021-12-07 CN disclosed